[HTML][HTML] Chemotherapy-induced neutropenia and emerging agents for prevention and treatment: a review

DW Blayney, L Schwartzberg - Cancer treatment reviews, 2022 - Elsevier
Highlights•Chemotherapy-induced neutropenia can lead to poor clinical outcomes.•CIN can
lead to infections, hospitalizations, mortality, and lower chemotherapy dose intensity.•G-CSF …

[HTML][HTML] New insight into strategies used to develop long-acting G-CSF biologics for neutropenia therapy

A Theyab, KF Alsharif, KJ Alzahrani, AAA Oyouni… - Frontiers in …, 2023 - frontiersin.org
Over the last 20 years, granulocyte colony-stimulating factors (G-CSFs) have become the
major therapeutic option for the treatment of patients with neutropenia. Most of the current G …

The impact of new and emerging agents on outcomes for febrile neutropenia: Addressing clinical gaps

J Crawford, C Oswalt - Current Opinion in Oncology, 2023 - journals.lww.com
Multiple emerging agents show promise in decreasing the burden of CIN. Use of these
therapies will reduce access disparities and will improve outcomes for patients with cancer …

[HTML][HTML] Analytical sameness methodology for the evaluation of structural, physicochemical, and biological characteristics of Armlupeg: A pegfilgrastim biosimilar case …

A Deshmukh, R Goyal, K Sundaram, K Dange… - Plos one, 2023 - journals.plos.org
Pegfilgrastim is administered as an adjunct to chemotherapy to reduce the incidence of
febrile neutropenia and associated infectious complications. Lupin's Pegfilgrastim is a …

Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic Acids, and Mammalian Cells in Safety Pharmacology

LR Brown - Drug Discovery and Evaluation: Safety and …, 2022 - Springer
The use of biomaterials to enable and enhance life-saving therapies in medicine has its
documented roots in the 1600s. Historically drugs were administered systemically for acute …