Candida auris Outbreaks: Current Status and Future Perspectives

S De Gaetano, A Midiri, G Mancuso, MG Avola… - Microorganisms, 2024 - mdpi.com
Candida auris has been identified by the World Health Organization (WHO) as a critical
priority pathogen on its latest list of fungi. C. auris infections are reported in the bloodstream …

[HTML][HTML] Connecting Cryptococcal Meningitis and Gut Microbiome

Y Ma, L Yang, M Jiang, X Zhao, P Xue - International Journal of Molecular …, 2023 - mdpi.com
Fungal pathogens of the Cryptococcus neoformans species complex (C. neoformans SC)
are a major cause of fungal meningitis in immunocompromised individuals. As with other …

Enhancing antifungal and biocompatible efficacy of undecanoic acid through incorporation with chitosan-based nanoemulsion

A Sathiyaseelan, X Zhang, K Han, MH Wang - International Journal of …, 2024 - Elsevier
The management of invasive fungal infections in humans poses significant challenges due
to the intricate nature of the treatment, which is both arduous and costly, necessitating …

Asymmetric Synthesis of Triazole Antifungal Agents Enabled by an Upgraded Strategy for the Key Epoxide Intermediate

Y Tang, Z Li, M Zeng, R Li, H Song… - The Journal of …, 2024 - ACS Publications
A streamlined and efficient approach to the key epoxide intermediate for the asymmetric
synthesis of triazole antifungal agents is presented. This synthesis highlights a P (NMe2) 3 …

[HTML][HTML] Combination of serum and peritoneal 1.3-beta-d-glucan can rule out intra-abdominal candidiasis in surgical critically ill patients: a multicenter prospective …

E Novy, J Rivière, M Nguyen, G Arfeuille, G Louis… - Critical Care, 2023 - Springer
Background Intra-abdominal candidiasis (IAC) is difficult to predict in critically ill patients with
intra-abdominal infection, leading to the overuse of antifungal treatments. Serum and …

Discovery of New Tricyclic Oxime Sampangine Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcosis and Candidiasis

W Yang, R Liu, Z Li, J Tu, D Xu, N Liu… - Journal of Medicinal …, 2024 - ACS Publications
Cryptococcus neoformans (C. neoformans) and Candida albicans (C. albicans) are
classified as the critical priority groups among the pathogenic fungi, highlighting the urgent …

[HTML][HTML] Recent Advances and Future Perspectives in Mitigating Invasive Antifungal-Resistant Pathogen Aspergillus fumigatus in Africa

CC Achilonu, A Davies, OO Kanu, CB Noel… - … Treatment Options in …, 2024 - Springer
Abstract Purpose of Review Azole resistance in Aspergillus fumigatus is an emerging public
health issue with global distribution and has been linked to use in agricultural and …

Mitigating amphotericin B cytotoxicity through gliadin-casein nanoparticles: Insights into synthesis, optimization, characterization, in vitro release and cytotoxicity …

RGV Marcano, NM Khalil, M de Lurdes Felsner… - International Journal of …, 2024 - Elsevier
Amphotericin B (AmB) is a widely used antifungal agent; however, its clinical application is
limited due to severe side effects and nephrotoxicity associated with parenteral …

[HTML][HTML] Uncovering the diversity of pathogenic invaders: insights into protozoa, fungi, and worm infections

R Shukla, J Soni, A Kumar, R Pandey - Frontiers in Microbiology, 2024 - frontiersin.org
Post COVID-19, there has been renewed interest in understanding the pathogens
challenging the human health and evaluate our preparedness towards dealing with health …

Utilization of Raman spectroscopy for identification and characterization of fungal pathogens

R Udupa, PP Yegneswaran, J Lukose… - Fungal Biology …, 2023 - Elsevier
Rapid and accurate identification of pathogens causing infections is one of the biggest
challenges of medicine. Timely identification and characterization of fungal pathogens is …