Acetaminophen (APAP) overdose can result in serious liver injury and potentially death.
Toxicity is dependent on metabolism of APAP to a reactive metabolite initiating a cascade of …

Mortality in colorectal cancer is associated with the development of liver metastases.
Surgical removal of these tumors is the only hope for cure, but recurrence is common …

INTRODUCTION: Elevation of total white blood cells (WBC) count is associated with higher
mortality in patients with acute coronary syndromes. However, it is unknown which specific …

A poorly controlled acute inflammatory response can lead to organ dysfunction and death.
Severe systemic inflammation can be induced and perpetuated by diverse insults such as …

I SCHEMIC and hypoxic liver injury are caused by absolute and relative deficiency of
oxygen, respectively. Ischemic liver injury occurs during storage of livers for transplantation …

Application desired functionality as well as operation expenses of cold atmospheric
pressure plasma (CAP) devices scale with properties like gas selection. The present …

Tumor necrosis factor (TNF) is released during hepatic ischemia/reperfusion (I/R) and plays
an important role in the ensuing neutrophil-mediated lung and liver injury. Since TNF is not a …

Ischemia-reperfusion (I/R) injury is an important mechanism of tissue destruction in a
number of diseases, including myocardial infarction, stroke, and crush injury. 1–4 …

Because of the lack of adequate organs, the number of patients with end-stage liver
diseases, acute liver failure or hepatic malignancies waiting for liver transplantation is …

Abstract IL-17-secreting T (Th17) cells play a protective role in certain bacterial infections,
but they are major mediators of inflammation and are pathogenic in organ-specific …