Abstract IL-17-secreting T (Th17) cells play a protective role in certain bacterial infections,
but they are major mediators of inflammation and are pathogenic in organ-specific …

Background: The liver has a number of functions in innate immunity. These functions
predispose the liver to innate immune-mediated liver injury when inflammation goes …

Cellular turnover is associated with exposure of surface phosphatidylserine (PS) in apoptotic
cells, leading to their phagocytic recognition and removal. But recent studies indicate that …

Objectives: The purpose of the present study was to examine the circulating levels of CXC-
chemokines in patients with various degree of congestive heart failure (CHF). Background …

Neutrophils are the most abundant type of leukocytes with diverse functions in immune
defense including production of reactive oxygen species, bacteriocidal proteins, neutrophil …

Osteopontin (OPN) is important for the function of fibroblasts, macrophages and lymphocytes
during inflammation and wound healing. In recent studies of experimental colitis we …

The presence of polymorphonuclear leukocytes (neutrophils) in liver parenchyma is a
prominent feature of alcoholic hepatitis. However, the pathophysiological importance of …

The emergence of organ system failure as the defining challenge in the management of the
critically ill mirrors the origins of the discipline of intensive care itself. Intensive care units …

The initiating step of neutrophil-induced cytotoxicity in the liver is the recruitment of these
phagocytes into sinusoids. The aim of our study was to compare the efficacy of systemic …

Background Paraquat is an effective and widely used herbicide but is also a lethal poison. In
many developing countries paraquat is widely available and inexpensive, making poisoning …