Colon cancer transcriptome

K Mokhtari, M Peymani, M Rashidi… - Progress in biophysics …, 2023 - Elsevier
Over the last four decades, methodological innovations have continuously changed
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …

Transcriptomic signatures in colorectal cancer progression

P Ershov, S Poyarkov, Y Konstantinova… - Current Molecular …, 2023 - ingentaconnect.com
Aims: Due to a large number of identified hub-genes encoding key molecular regulators,
which are involved in signal transduction and metabolic pathways in cancers, it is relevant to …

Novel diagnostic and prognostic biomarkers of colorectal cancer: capable to overcome the heterogeneity-specific barrier and valid for global applications

Y Hameed, M Usman, S Liang, S Ejaz - PLoS One, 2021 - journals.plos.org
Introduction The heterogeneity-specific nature of the available colorectal cancer (CRC)
biomarkers is significantly contributing to the cancer-associated high mortality rate …

Identification of key gene targets for sensitizing colorectal cancer to chemoradiation: an integrative network analysis on multiple transcriptomics data

H Manoochehri, A Jalali, H Tanzadehpanah… - Journal of …, 2022 - Springer
Purpose Colorectal cancer (CRC) is a main cause of morbidity and mortality in the world.
Chemoradioresistance is a major problem in CRC treatment. Identification of novel …

Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents

MA Horaira, MA Islam, MK Kibria, MJ Alam… - BMC Medical …, 2023 - Springer
Background Detection of appropriate receptor proteins and drug agents are equally
important in the case of drug discovery and development for any disease. In this study, an …

Integrating network pharmacology approaches for the investigation of multi-target pharmacological mechanism of 6-shogaol against cervical cancer

AM Elasbali, WA Al-Soud… - Journal of …, 2023 - Taylor & Francis
Traditional treatment of cancer has been plagued by a number of obstacles, such as multiple
drug resistance, toxicity and financial constraints. In contrast, phytochemicals that modulate …

A network-based pharmacological investigation to identify the mechanistic regulatory pathway of andrographolide against colorectal cancer

B Janani, M Vijayakumar, K Priya, JH Kim… - Frontiers in …, 2022 - frontiersin.org
Traditional cancer treatments have posed numerous obstacles, including toxicity, multiple
drug resistance, and financial cost. On the contrary, bioactive phytochemicals used in …

[HTML][HTML] Comprehensive analysis of the prognosis and immune infiltration for CXC chemokines in colorectal cancer

X Yang, Y Wei, F Sheng, Y Xu, J Liu, L Gao… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
The CXC motif (CXC) chemokines are a family of chemotactic molecules that have been
identified as potential prognostic markers and prospective therapeutic targets for many kinds …

CDC25A is strongly associated with colorectal cancer stem cells and poor clinical outcome of patients

H Manoochehri, S Asadi, H Tanzadehpanah… - Gene Reports, 2021 - Elsevier
Background and aim Cancer stem cells (CSCs) are essential challenge in recurrence-free
treatment of colorectal cancer (CRC) Patients. Targeting CSCs related genes can provide …

Antioxidative and ROS-dependent apoptotic effects of Cuscuta reflexa Roxb. stem against human lung cancer: network pharmacology and in vitro experimental …

AM Elasbali, WA Al-Soud… - Journal of …, 2023 - Taylor & Francis
Lung cancer remains a formidable global health challenge, necessitating the exploration of
novel therapeutic approaches. This study investigates the potential of Cuscuta reflexa Roxb …