Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strains

CM Lin, LJ Saif, D Marthaler, Q Wang - Virus research, 2016 - Elsevier
Emerging and re-emerging coronaviruses cause morbidity and mortality in human and
animal populations, resulting in serious public and animal health threats and economic …

[HTML][HTML] In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM

CY Huang, P Draczkowski, YS Wang, CY Chang… - Nature …, 2022 - nature.com
Porcine epidemic diarrhea (PED) is a highly contagious swine disease caused by porcine
epidemic diarrhea virus (PEDV). PED causes enteric disorders with an exceptionally high …

Porcine epidemic diarrhea virus: current insights

C Lv, Y Xiao, X Li, K Tian - Virus adaptation and treatment, 2016 - Taylor & Francis
Porcine epidemic diarrhea virus (PEDV), an enveloped, single-stranded, positive-sense
RNA virus belonging to the genus Alphacoronavirus in the family Coronaviridae, can infect …

[HTML][HTML] Identification of neutralizing monoclonal antibodies targeting novel conformational epitopes of the porcine epidemic diarrhoea virus spike protein

CY Chang, IC Cheng, YC Chang, PS Tsai, SY Lai… - Scientific reports, 2019 - nature.com
Since 2010, newly identified variants of porcine epidemic diarrhoea virus (PEDV) have
caused high mortality in neonatal piglets which has devastated the swine industry. The spike …

Two novel porcine epidemic diarrhea virus (PEDV) recombinants from a natural recombinant and distinct subtypes of PEDV variants

N Chen, S Li, R Zhou, M Zhu, S He, M Ye, Y Huang… - Virus Research, 2017 - Elsevier
Porcine epidemic diarrhea virus (PEDV) causes devastating impact on global pig-breeding
industry and current vaccines have become not effective against the circulating PEDV …

[HTML][HTML] Isolation and identification of a recombinant porcine epidemic diarrhea virus with a novel insertion in S1 domain

D Li, Y Li, Y Liu, Y Chen, W Jiao, H Feng… - Frontiers in …, 2021 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) is the major pathogen that causes diarrhea and
high mortality in newborn piglets with devastating impact to the pig industry. Recombination …

[HTML][HTML] Display of porcine epidemic diarrhea virus spike protein on baculovirus to improve immunogenicity and protective efficacy

CY Chang, WT Hsu, YC Chao, HW Chang - Viruses, 2018 - mdpi.com
A new variant of the porcine epidemic diarrhea virus (PEDV) is an emerging swine disease,
killing considerable numbers of neonatal piglets in North America and Asia in recent years …

Molecular characterization of porcine epidemic diarrhea virus associated with outbreaks in southwest China during 2014–2018

Y Tian, X Yang, H Li, B Ma, R Guan… - Transboundary and …, 2021 - Wiley Online Library
Porcine epidemic diarrhea virus (PEDV), which re‐emerged in China since 2010, has swept
across the whole country leading to tremendous economic losses. In this study, a total of 645 …

Prevalence and phylogenetic analysis of spike gene of porcine epidemic diarrhea virus in Henan province, China in 2015–2019

H Zhang, F Han, X Yan, L Liu, X Shu, H Hu - Infection, Genetics and …, 2021 - Elsevier
Porcine epidemic diarrhea virus (PEDV) causes diarrhea, dehydration and a high morbidity
and mortality in piglets. To investigate the prevalence and molecular characteristics of the …

[HTML][HTML] Efficacy of heat-labile enterotoxin B subunit-adjuvanted parenteral porcine epidemic diarrhea virus trimeric spike subunit vaccine in piglets

YC Chang, CY Chang, PS Tsai, HY Chiou… - Applied microbiology …, 2018 - Springer
Devastating outbreaks of porcine epidemic diarrhea (PED) started in China in late 2010 and
rapidly spread to North America and Asia causing severe diarrhea and high mortality in …