Hijacking of the AP-1 signaling pathway during development of ATL

H Gazon, B Barbeau, JM Mesnard… - Frontiers in …, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy
known as adult T-cell leukemia (ATL). One way to address the pathology of the disease lies …

HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

HIV-1 and HTLV-1 transmission modes: Mechanisms and importance for virus spread

S Kalinichenko, D Komkov, D Mazurov - Viruses, 2022 - mdpi.com
So far, only two retroviruses, human immunodeficiency virus (HIV)(type 1 and 2) and human
T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans …

Cytokine networks dysregulation during HTLV-1 infection and associated diseases

N Futsch, G Prates, R Mahieux, J Casseb, H Dutartre - Viruses, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic
inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses

TH Mulherkar, DJ Gómez, G Sandel, P Jain - Viruses, 2022 - mdpi.com
Dendritic cells (DCs) function as a link between innate and adaptive immune responses.
Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to …

HTLV-1 infection and pathogenesis: new insights from cellular and animal models

G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …

Advances in preventive vaccine development against HTLV-1 infection: A systematic review of the last 35 years

CS Santana, FO Andrade, GCS da Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction The Human T-lymphotropic virus type 1 (HTLV-1) was the first described human
retrovirus. It is currently estimated that around 5 to 10 million people worldwide are infected …

Inhibition of tunneling nanotube (TNT) formation and human T-cell leukemia virus type 1 (HTLV-1) transmission by cytarabine

M Omsland, C Pise-Masison, D Fujikawa, V Galli… - Scientific Reports, 2018 - nature.com
The human T-cell leukemia virus type 1 (HTLV-1) is highly dependent on cell-to-cell
interaction for transmission and productive infection. Cell-to-cell interactions through the …

Specialized intercellular communications via tunnelling nanotubes in acute and chronic leukemia

A Allegra, M Di Gioacchino, G Cancemi, M Casciaro… - Cancers, 2022 - mdpi.com
Simple Summary Tunneling nanotubes (TNTs) are cytoplasmic channels which regulate the
contacts between cells and allow the transfer of several elements, including ions …

HTLV-1 infection of myeloid cells: from transmission to immune alterations

B Rocamonde, A Carcone, R Mahieux, H Dutartre - Retrovirology, 2019 - Springer
Human T cell leukemia virus type 1 (HTLV-1), the etiological agent of adult T-cell
leukemia/lymphoma (ATLL) and the demyelinating neuroinflammatory disease known as …