Most pathogens access the body through the mucosal membranes. Therefore, effective
vaccines that protect at these sites are much needed. However, despite early success with …

Zimbabwe offers the most recent example of the tragedy that befalls a country and its people
when cholera strikes. The 2008–2009 outbreak rapidly spread across every province and …

SUMMARY ETEC is an underrecognized but extremely important cause of diarrhea in the
developing world where there is inadequate clean water and poor sanitation. It is the most …

Findings from the field of evolutionary biology are yielding dramatic insights for health
scientists, especially those involved in the fight against infectious diseases. This book is the …

More recently, however, there have occurred great advances in our knowledge of the patho-
genesis of infections due to these bacterial enteropathogens. This new information has been …

Biological activity of bovine κ-caseino glycomacropeptide (GMP) has received much
attention in recent years. Research has focused on the ability of GMP to bind cholera and …

Vibrio cholerae is a Gram-negative bacterial pathogen that consists of over 200 serogroups
with differing pathogenic potential. Only strains that express the virulence factors cholera …

Antigen-specific B cell responses to mucosally delivered proteins are dependent upon CD4-
positive T helper (Th) cells, and the frequency of Th1 and Th2 cell responses after oral …

After De's pivotal demonstration in 1959 of a diarrhoeogenic exo-enterotoxin in cell-free
culture filtrates from Vibrio cholerae (of classical biotype), much insight has been gained …

Most secreted and cell membrane proteins in mammals are glycosylated. Many of these
glycoproteins are also prevalent in milk and play key roles in the biomodulatory properties of …