[HTML][HTML] Ferroptosis and PPAR-gamma in the limelight of brain tumors and edema
E Yakubov, S Schmid, A Hammer, D Chen… - Frontiers in …, 2023 - frontiersin.org
Human malignant brain tumors such as gliomas are devastating due to the induction of
cerebral edema and neurodegeneration. A major contributor to glioma-induced …
cerebral edema and neurodegeneration. A major contributor to glioma-induced …
Repurposing of pexidartinib for microglia depletion and renewal
MP Weyer, J Strehle, MKE Schäfer, I Tegeder - Pharmacology & …, 2023 - Elsevier
Pexidartinib (PLX3397) is a small molecule receptor tyrosine kinase inhibitor of colony
stimulating factor 1 receptor (CSF1R) with moderate selectivity over other members of the …
stimulating factor 1 receptor (CSF1R) with moderate selectivity over other members of the …
Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma
Abstract Background Glioblastomas (GBMs) are central nervous system tumors that resist
standard-of-care interventions and even immune checkpoint blockade. Myeloid cells in the …
standard-of-care interventions and even immune checkpoint blockade. Myeloid cells in the …
The ins and outs of microglial cells in brain health and disease
C Pallarés-Moratalla, G Bergers - Frontiers in Immunology, 2024 - frontiersin.org
Microglia are the brain's resident macrophages that play pivotal roles in immune
surveillance and maintaining homeostasis of the Central Nervous System (CNS). Microglia …
surveillance and maintaining homeostasis of the Central Nervous System (CNS). Microglia …
Rotor-based image-guided therapy of glioblastoma
Z Pan, Y Zeng, Z Ye, Y Li, Y Wang, Z Feng… - Journal of Controlled …, 2024 - Elsevier
Glioblastoma (GBM), deep in the brain, is more challenging to diagnose and treat than other
tumors. Such challenges have blocked the development of high-impact therapeutic …
tumors. Such challenges have blocked the development of high-impact therapeutic …
A novel disulfidptosis-related gene signature predicts overall survival of glioblastoma patients
Y Zhang, B Liu, Y Zhou - Future Science OA, 2024 - Taylor & Francis
Aim: The aim of this study was to investigate the prognostic relevance of disulfidptosis-
related genes in glioblastoma using bioinformatic analysis in The Cancer Genome Atlas …
related genes in glioblastoma using bioinformatic analysis in The Cancer Genome Atlas …