[HTML][HTML] New perspectives in food allergy

M De Martinis, MM Sirufo, M Suppa… - International journal of …, 2020 - mdpi.com
The improvement of the knowledge of the pathophysiological mechanisms underlying the
tolerance and sensitization to food antigens has recently led to a radical change in the …

[HTML][HTML] Sex and gender aspects for patient stratification in allergy prevention and treatment

M De Martinis, MM Sirufo, M Suppa… - International journal of …, 2020 - mdpi.com
Allergies are rapidly worsening in recent decades, representing the most common
immunological diseases. The mechanism of disorders such as asthma, rhinocongiuntivitis …

Osteoporosis: Current and emerging therapies targeted to immunological checkpoints

M De Martinis, MM Sirufo… - Current medicinal …, 2020 - ingentaconnect.com
Osteoporosis is a skeletal pathology characterized by compromised bone strength leading
to increased risk of fracture, mainly the spine and hip fractures. Osteoporosis affects more …

[HTML][HTML] Osteoporosis from an endocrine perspective: the role of hormonal changes in the elderly

R Cannarella, F Barbagallo, RA Condorelli… - Journal of clinical …, 2019 - mdpi.com
Introduction: Osteoporosis is increasingly prevalent in the elderly, with fractures mostly
occurring in women and men who are older than 55 and 65 years of age, respectively. The …

[HTML][HTML] The osteoporosis/microbiota linkage: the role of miRNA

M De Martinis, L Ginaldi, A Allegra, MM Sirufo… - International journal of …, 2020 - mdpi.com
Hundreds of trillions of bacteria are present in the human body in a mutually beneficial
symbiotic relationship with the host. A stable dynamic equilibrium exists in healthy …

[HTML][HTML] Hyperhomocysteinemia is associated with inflammation, bone resorption, vitamin B12 and folate deficiency and MTHFR C677T polymorphism in …

M De Martinis, MM Sirufo, C Nocelli… - International journal of …, 2020 - mdpi.com
Osteoporosis is an age-related bone disease, affecting mainly postmenopausal women,
characterized by decreased bone mineral density (BMD) and consequent risk of fractures …

[HTML][HTML] Alarmins in osteoporosis, RAGE, IL-1, and IL-33 pathways: a literature review

M De Martinis, L Ginaldi, MM Sirufo, G Pioggia… - Medicina, 2020 - mdpi.com
Alarmins are endogenous mediators released by cells following insults or cell death to alert
the host's innate immune system of a situation of danger or harm. Many of these, such as …

[HTML][HTML] IL-33/IL-31 axis in osteoporosis

M De Martinis, MM Sirufo, M Suppa… - International journal of …, 2020 - mdpi.com
The study of the immunoskeletal interface has led to the discovery of numerous cytokines
involved in the regulation of bone remodeling, providing valuable information on the …

A novel BMP2 secretagogue ameliorates glucocorticoid induced oxidative stress in osteoblasts by activating NRF2 dependent survival while promoting Wnt/β-catenin …

D Rai, AK Tripathi, A Sardar, AR Pandey… - Free Radical Biology …, 2022 - Elsevier
In our previous study, a novel BMP2 secretagogue was synthesized belonging to a class of
galloyl conjugates of flavanones, with remarkable osteogenic potential that promoted bone …

[HTML][HTML] Osteoporosis in skin diseases

MM Sirufo, F De Pietro, EM Bassino, L Ginaldi… - International Journal of …, 2020 - mdpi.com
Osteoporosis (OP) is defined as a generalized skeletal disease characterized by low bone
mass and an alteration of the microarchitecture that lead to an increase in bone fragility and …