Synthesis of 11C, 18F, 15O, and 13N Radiolabels for Positron Emission Tomography

PW Miller, NJ Long, R Vilar… - Angewandte Chemie …, 2008 - Wiley Online Library
Positron emission tomography (PET) is a powerful and rapidly developing area of molecular
imaging that is used to study and visualize human physiology by the detection of positron …

Radiopharmaceutical chemistry for positron emission tomography

Z Li, PS Conti - Advanced drug delivery reviews, 2010 - Elsevier
Molecular imaging is an emerging technology that allows the visualization of interactions
between molecular probes and biological targets. Molecules that either direct or are subject …

Subregional patterns of preferential striatal dopamine transporter loss differ in Parkinson disease, progressive supranuclear palsy, and multiple-system atrophy

M Oh, JS Kim, JY Kim, KH Shin, SH Park… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Parkinson disease (PD), progressive supranuclear palsy (PSP), and multiple-system atrophy
(MSA) are known to affect dopaminergic neurons of the brain stem and striatum with different …

Radiosyntheses using fluorine-18: the art and science of late stage fluorination

EL Cole, MN Stewart, R Littich… - Current topics in …, 2014 - ingentaconnect.com
Positron (β+) emission tomography (PET) is a powerful, noninvasive tool for the in vivo, three-
dimensional imaging of physiological structures and biochemical pathways. The continued …

Fluorine-18 radiopharmaceuticals beyond [18F] FDG for use in oncology and neurosciences

HH Coenen, PH Elsinga, R Iwata, MR Kilbourn… - Nuclear medicine and …, 2010 - Elsevier
Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide
thanks to the availability of compact medical cyclotrons and automated chemistry for the …

Recent developments and trends in 18F-radiochemistry: syntheses and applications

R Schirrmacher, C Wangler… - Mini-Reviews in …, 2007 - ingentaconnect.com
In this short review we describe recent methods and novel trends for the introduction of
fluorine-18 into molecules which in turn are intended to serve as imaging agents for the in …

Synthese von 11C‐, 18F‐, 15O‐und 13N‐Radiotracern für die Positronenemissionstomographie

PW Miller, NJ Long, R Vilar, AD Gee - Angewandte Chemie, 2008 - Wiley Online Library
Die Positronenemissionstomographie (PET) ist eine leistungsfähige Bildgebungsmethode,
die zur Untersuchung und Visualisierung der menschlichen Physiologie eingesetzt wird …

[HTML][HTML] Microfluidics: a groundbreaking technology for PET tracer production?

C Rensch, A Jackson, S Lindner, R Salvamoser… - Molecules, 2013 - mdpi.com
Application of microfluidics to Positron Emission Tomography (PET) tracer synthesis has
attracted increasing interest within the last decade. The technical advantages of …

Evaluation of the neuroprotective effect of microglial depletion by CSF-1R inhibition in a Parkinson's animal model

SJ Oh, H Ahn, KH Jung, SJ Han, KR Nam… - Molecular imaging and …, 2020 - Springer
Abstract Purpose Neuroinflammation in Parkinson's disease (PD) is known to play a pivotal
role in progression to neuronal degeneration. It has been reported that colony-stimulation …

[HTML][HTML] Natural product-based radiopharmaceuticals: Focus on curcumin and its analogs, flavonoids, and marine peptides

H Wongso - Journal of Pharmaceutical Analysis, 2022 - Elsevier
Natural products provide a bountiful supply of pharmacologically relevant precursors for the
development of various drug-related molecules, including radiopharmaceuticals. However …