Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis

JN Jarvis, A Percival, S Bauman… - Clinical infectious …, 2011 - academic.oup.com
Background. Many deaths from cryptococcal meningitis (CM) may be preventable through
early diagnosis and treatment. An inexpensive point-of-care (POC) assay for use with urine …

The continuing burden of advanced HIV disease over 10 years of increasing antiretroviral therapy coverage in South Africa

M Osler, K Hilderbrand, E Goemaere… - Clinical Infectious …, 2018 - academic.oup.com
Background Antiretroviral treatment (ART) has been massively scaled up to decrease
human immunodeficiency virus (HIV)–related morbidity, mortality, and HIV transmission …

[HTML][HTML] Comparison of cryptococcal antigenemia between antiretroviral naïve and antiretroviral experienced HIV positive patients at two hospitals in Ethiopia

T Beyene, Y Woldeamanuel, D Asrat, G Ayana… - PLoS …, 2013 - journals.plos.org
Background Cryptococcal meningitis is a major cause of HIV/AIDS-related deaths in Africa.
Cryptococcosis is a neglected killer. However, meningitis can be prevented by early …

Rapid diagnosis of cryptococcal meningitis by use of lateral flow assay on cerebrospinal fluid samples: influence of the high-dose “hook” effect

A Lourens, JN Jarvis, G Meintjes… - Journal of clinical …, 2014 - Am Soc Microbiol
Cryptococcal meningitis is the most frequent cause of meningitis and a major cause of
mortality in HIV-infected adults in Africa. This study evaluated the performance of the lateral …

Neuroimaging of HIV-associated cryptococcal meningitis: comparison of magnetic resonance imaging findings in patients with and without immune reconstitution

J Katchanov, G Branding, L Jefferys… - … journal of STD & …, 2016 - journals.sagepub.com
To determine the frequency, imaging characteristics, neuroanatomical distribution and
dynamics of magnetic resonance imaging findings in HIV-associated cryptococcal …

[HTML][HTML] The repurposing of anti-psychotic drugs, quetiapine and olanzapine, as anti-cryptococcus drugs

AO Ogundeji, CH Pohl, OM Sebolai - Frontiers in Microbiology, 2017 - frontiersin.org
The management of cryptococcal infections is often difficult. This can, in part, be attributed to
the fungistatic nature of fluconazole, which may result in cells disseminating to give rise to …

Cryptococcosis in HIV-infected hospitalized patients in Germany: Evidence for routine antigen testing

J Katchanov, L Jefferys, D Tominski, K Wöstmann… - Journal of Infection, 2015 - Elsevier
Objectives To investigate the diagnostic value of routine cryptococcal antigen (CRAG)
testing in HIV-infected patients in a low prevalence setting. Methods Retrospective single …

The aetiologies, clinical presentation, diagnostic difficulties and outcomes of meningitis among HIV-positive adults admitted to Livingstone hospital, Port Elizabeth

KD Dele-Ijagbulu - 2019 - etd.uwc.ac.za
Meningitis is a common opportunistic infection and an important cause of mortality among
people living with HIV and AIDS globally. This study investigated meningitis in adults living …

[PDF][PDF] The repurposing of chemical compounds as anti-Cryptococcus drugs

AO Ogundeji - 2017 - scholar.ufs.ac.za
English: The manifestation of disseminated cryptococcal infection in HIV-infected individual
is a life-threatening infection, with 70% mortality rate in sub-Saharan Africa. People are …

[引用][C] Rapid diagnosis of cryptococcal meningitis using the lateral flow assay on CSF samples: the influence of the high dose “hook” effect. 2

A Lourens, JN Jarvis, G Meintjes, CM Samuel - 2014