Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide.
Early prevention with HPV vaccination is a safe and effective method against this disease …

Adoptive T-cell therapy can target and kill widespread malignant cells thereby inducing
durable clinical responses in melanoma and selected other malignances. However, many …

Adoptive transfer of T cells genetically modified to express a cancer-specific T-cell receptor
(TCR) has shown significant therapeutic potential for both hematological and solid tumors …

A subset of human papillomaviruses (HPVs) promote anogenital malignancy, including
cervical cancer, and prevention and treatment strategies that reflect the causal role of HPV …

Abstract T cell receptor (TCR) T cell therapy is a promising cancer treatment modality.
However, its successful development for epithelial cancers may depend on the identification …

Abstract Purpose: The E6 and E7 oncoproteins of HPV-associated epithelial cancers are in
principle ideal immunotherapeutic targets, but evidence that T cells specific for these …

Tumour-associated viruses produce antigens that, on the face of it, are ideal targets for
immunotherapy. Unfortunately, these viruses are experts at avoiding or subverting the host …

Human papillomavirus (HPV) is the most frequently sexually transmitted agent in the world. It
can cause cervical and other anogenital malignancies, and oropharyngeal cancer. HPV has …

Infection with human papillomaviruses (HPV) is known to play a central role in the
development of cervical cancer. Both host and viral genetic factors have been postulated to …

The greatest risk factor for the development of cervical and other cancers that have been
linked to the human papillomavirus (HPV) family is the persistence of the virus. To persist for …