Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation …

The kidneys operate at the interface of plasma and urine by clearing molecular waste
products while retaining valuable solutes. Genetic studies of paired plasma and urine …

Summary 10 years ago, a detailed analysis showed that only 33% of genome-wide
association study (GWAS) results included the X chromosome. Multiple recommendations …

Pharmacogenomic (PGx) testing has emerged as a compelling strategy that clinicians can
use to inform antidepressant medication selection and dosing, but the clinical efficacy of this …

Abstract Purpose The Mayo-Baylor RIGHT 10K Study enabled preemptive, sequence-based
pharmacogenomics (PGx)-driven drug prescribing practices in routine clinical care within a …

Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …

The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C9 gene. Genetic variation within the …

In Dr. Francis Collins' 2001 testimony to Congress, he heralded advances in genetics with
the Human Genome Project. He imagined testing “being used to tailor medicines to fit …

Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug
selection and dosing to the patient's genetic features. In recent years, several …