The pathologies of many infectious, autoimmune and malignant diseases are influenced by
the profiles of cytokine production in pro-inflammatory (TH1) and anti-inflammatory (TH2) T …

Human leukocyte antigens (HLAs) are widely expressed cell surface molecules which
present antigenic peptides to T‐lymphocytes, thus modulating the immune response. The …

BACKGROUND: Previous research has demonstrated that many lung cancer survivors
report difficulties with symptom control and experience a poor quality of life (QOL). Although …

Purpose Cytokine milieu of tumor microenvironment affects tumorigenesis in breast cancer.
The aim of the present study was to investigate the potential association of functional single …

We conducted a meta-analysis to assess the association between tumor necrosis factor-
alpha (TNF-alpha) gene TNFA− 308 (G> A), TNFA− 238 (G> A), TNFA− 857 (C> T), TNFA …

We assayed for germline single nucleotide polymorphisms (SNPs) in the TNFB and TNFA
genes in patients with breast cancer. SNPs were observed in the first intron of TNFB (G/A) …

The objective of this study was to investigate the contribution of the tumor necrosis factor-α
(TNF-α) gene polymorphisms to recurrent spontaneous abortion (RSA). The study …

We examined the relationship between the NcoI RFLP of tumor necrosis factor beta (TNFB)
and alpha (TNFA) genes and the risk of colorectal cancer. The first intron of TNFB and the …

Cutaneous malignant melanoma (CMM) is a potentially fatal malignancy in which exposure
to UV light is the most important risk factor. Several lines of evidence suggest that increased …

Background: The multifunctional cytokines of the tumor necrosis factor (TNF) family have
been found to be involved in the promotion of inflammatory responses, and to play critical …