The emergence of antimicrobial resistance against Mycobacterium tuberculosis, the leading
cause of mortality due to a single microbial pathogen worldwide, represents a growing threat …

Summary Background The Xpert MTB/RIF assay is an automated molecular test that has
improved the detection of tuberculosis and rifampicin resistance, but its sensitivity is …

Tuberculosis (TB) remains one of the most important causes of death among people co‐
infected with human immunodeficiency virus (HIV). The diagnosis of TB remains challenging …

Tuberculosis, disease caused by Mycobacterium tuberculosis, is currently the leading cause
of death by a single infectious agent worldwide. Early, rapid and accurate identification of M …

More sensitive tests are needed for the diagnosis of smear-negative and HIV-associated
tuberculosis. This study compares the sensitivities and specificities of three molecular tests …

In this review, we describe diagnostic strategies specifically for HIV and TB co-infected
individuals. Molecular diagnostics in particular within the past 5 years have revolutionized …

Background Rapid and accurate diagnosis of tuberculosis (TB) is key to manage the
disease and to control and prevent its transmission. Many established diagnostic methods …

Various diagnostic companies have developed high throughput molecular assays for
tuberculosis (TB) and resistance detection for rifampicin and isoniazid. We performed a …

Bacterial acute pneumonia is responsible for an extremely large burden of death worldwide
and diagnosis is paramount in the management of patients. While multidrug-resistant …

South Africa is a country with a high incidence of tuberculosis (TB), complicated by
coinfection with human immunodeficiency virus (HIV). The Xpert MTB/RIF (Cepheid …