[HTML][HTML] Counter-regulatory renin–angiotensin system in cardiovascular disease
M Paz Ocaranza, JA Riquelme, L García… - Nature Reviews …, 2020 - nature.com
The renin–angiotensin system is an important component of the cardiovascular system.
Mounting evidence suggests that the metabolic products of angiotensin I and II—initially …
Mounting evidence suggests that the metabolic products of angiotensin I and II—initially …
Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
[HTML][HTML] Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine
JC Contreras-Naranjo, HJ Wu, VM Ugaz - Lab on a Chip, 2017 - pubs.rsc.org
Exosomes, the smallest sized extracellular vesicles (∽ 30–150 nm) packaged with lipids,
proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their …
proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their …
Extracellular vesicles in angiogenesis
D Todorova, S Simoncini, R Lacroix, F Sabatier… - Circulation …, 2017 - Am Heart Assoc
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
Comparison of small extracellular vesicles isolated from plasma by ultracentrifugation or size-exclusion chromatography: yield, purity and functional potential
Interest in small extracellular vesicles (sEVs) as functional carriers of proteins and nucleic
acids is growing continuously. There are large numbers of sEVs in the blood, but lack of …
acids is growing continuously. There are large numbers of sEVs in the blood, but lack of …
[HTML][HTML] A comparative study of serum exosome isolation using differential ultracentrifugation and three commercial reagents
Exosomes play a role in cell-to-cell signaling and serve as possible biomarkers. Isolating
exosomes with reliable quality and substantial concentration is a major challenge. Our …
exosomes with reliable quality and substantial concentration is a major challenge. Our …
MSC exosome as a cell-free MSC therapy for cartilage regeneration: implications for osteoarthritis treatment
Mesenchymal stem cell (MSC) therapies have demonstrated efficacy in cartilage repair in
animal and clinical studies. The efficacy of MSC-based therapies which was previously …
animal and clinical studies. The efficacy of MSC-based therapies which was previously …
[HTML][HTML] Neutrophils in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus: same foe different MO
M Fresneda Alarcon, Z McLaren, HL Wright - Frontiers in immunology, 2021 - frontiersin.org
Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …
Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European …
Extracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting
considerable interest in the cardiovascular field as the wide range of their functions is …
considerable interest in the cardiovascular field as the wide range of their functions is …