Enzymes are excellent catalysts that are increasingly being used in industry and academia.
This perspective is primarily aimed at synthetic organic chemists with limited experience …

Even though enzymes are the cornerstones of living systems, it has so far proven difficult to
deploy artificial catalysts in a biological setting. Organocatalysts are arguably well-suited …

We report here a stereodivergent method for the Michael addition of aryl acetic acid esters to
α, β-unsaturated aldehydes catalyzed by a combination of a chiral pyrrolidine and a chiral …

Organic reactions that occur at the water interface for water-insoluble compounds, and
reactions in water solution for water soluble compounds, has added a powerful dimension to …

In the area of asymmetric organocatalysis, significant effort has been dedicated during the
last decade to improve the performance of emblematic catalysts such as proline, as well as …

In recent years, sustainable organocatalysis has become a relevant target in asymmetric
organic synthesis. Among the most successful strategies to achieve “greener” …

The development of CC and C-heteroatom (CN, CO and CP) bond reactions is a field of
significant interest and has received momentous attention in modern organic chemistry …

Asymmetric organocatalysis often operates under near ambient conditions, which means it
is air and moisture compatible. However, in many examples water is indeed necessary for …

Bisenols and its derivatives are attractive heterocyclic compounds exhibiting a wide range of
biological properties, including anticancer, antipyretic and antimicrobial characteristics …

The minimization of generation of wastes or their eradication is a crucial aspect of Green
Chemistry. As such, the design of processes that involve any or both the two, is of utmost …