The heterogeneity of asthma makes it challenging to unravel the pathophysiologic
mechanisms of the disease. Despite the wealth of research identifying diverse phenotypes …

Earlier research has presumed that the male and female biology is similar in most organs
except the reproductive system, leading to major misconceptions in research interpretations …

Investigation of gene‐environment interactions (GxE) may provide important insights into the
gene regulatory framework in response to environmental factors of relevance for childhood …

Background: Climate change's influence on extreme weather events poses a significant
threat to the morbidity and mortality of asthma patients. The aim of this study was to examine …

Sex differences in susceptibility, severity, and progression are prevalent for various diseases
in multiple organ systems. This phenomenon is particularly apparent in respiratory diseases …

Background Adult-onset asthma is associated with a poor treatment response. The aim was
to study associations between clinical characteristics, asthma control and treatment in adult …

The airway epithelial barrier is crucial for defending against respiratory insults and diseases.
Disruption of epithelial integrity contributes to respiratory diseases, and sex-specific …

Polygenic scores (PGSs) offer the ability to predict genetic risk for complex diseases across
the life course; a key benefit over short-term prediction models. To produce risk estimates …

Asthma is characterized by an increase in the contraction and inflammation of airway
muscles, resulting in airflow obstruction. The prevalence of asthma is lower in females than …

Background: Cross-sectional evidence has suggested a high prevalence of atopic diseases
in patients with hidradenitis suppurativa (HS). However, there is a lack of evidence based on …