Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle

X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …

[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery

VP Chavda, A Pandya, L Kumar, N Raval, LK Vora… - Nano Today, 2023 - Elsevier
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis

XY Huang, ZL Huang, J Huang, B Xu… - Journal of Experimental …, 2020 - Springer
Background Exosomes play crucial roles in regulating the crosstalk between normal and
cancer cells in the tumor microenvironment, and in regulating cancer proliferation, migration …

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

J Kowal, G Arras, M Colombo… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) have become the focus of rising interest because of their
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …

Extracellular vesicle isolation and characterization: toward clinical application

R Xu, DW Greening, HJ Zhu… - The Journal of …, 2016 - Am Soc Clin Investig
Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …

Biological functions and current advances in isolation and detection strategies for exosome nanovesicles

K Boriachek, MN Islam, A Möller, C Salomon… - Small, 2018 - Wiley Online Library
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …

Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non–small cell lung cancer using next-generation sequencing

X Jin, Y Chen, H Chen, S Fei, D Chen, X Cai, L Liu… - Clinical cancer …, 2017 - AACR
Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …