Exosomes as a new frontier of cancer liquid biopsy
D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer
X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …
Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle
X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …
multistep endocytosis process and carry diverse functional molecular cargoes, including …
[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics
A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …
plasma membrane fuse and are released into the surrounding body fluids. They are best …
Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis
XY Huang, ZL Huang, J Huang, B Xu… - Journal of Experimental …, 2020 - Springer
Background Exosomes play crucial roles in regulating the crosstalk between normal and
cancer cells in the tumor microenvironment, and in regulating cancer proliferation, migration …
cancer cells in the tumor microenvironment, and in regulating cancer proliferation, migration …
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
J Kowal, G Arras, M Colombo… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) have become the focus of rising interest because of their
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …
Extracellular vesicle isolation and characterization: toward clinical application
Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …
Biological functions and current advances in isolation and detection strategies for exosome nanovesicles
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …
Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non–small cell lung cancer using next-generation sequencing
X Jin, Y Chen, H Chen, S Fei, D Chen, X Cai, L Liu… - Clinical cancer …, 2017 - AACR
Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …