In the pursuit of improved treatments for Parkinson's disease (PD), the adenosine A2A
receptor has emerged as an attractive nondopaminergic target. Based on the compelling …

Pathological and neuroimaging studies have shown that in Parkinson's disease (PD) there
is a “subclinical” or “premotor” period during which dopaminergic neurons in the substantia …

Psychiatric disorders are common in many neurological disorders, including epilepsy,
migraine, Alzheimer's disease, Parkinson's disease, essential tremor, and stroke. These …

Objective: To evaluate the risk of Parkinson disease (PD) among patients with depression by
using the Taiwan National Health Insurance Research Database (NHIRD). Methods: We …

There is growing evidence that a variety of symptoms can precede the classical motor
features of Parkinson's disease (PD). The period when these symptoms arise can be …

Parkinsonism is a clinical syndrome characterized by bradykinesia, hypo-/akinesia,
muscular rigidity, and resting tremor, mainly caused by Parkinson's disease (PD) …

OBJECTIVE: To assess the relationship between depression and anxiety and Parkinson's
disease (PD). BACKGROUND: Many people with PD suffer from depression and anxiety …

The non-motor symptoms (NMS) of Parkinson's disease (PD) are often poorly recognized
and inadequately treated in contrast to motor symptoms and a modern holistic approach to …

Depression in Parkinson's disease (PD) is common, but little is known about its recognition
and treatment. The authors report the antidepressant experience (N= 100) and outcome of …

Non motor symptoms (NMS) of PD are a key determinant of health, quality of life and societal
cost of PD. Contrary to common perception, many NMS of PD occur early in PD and some …