The brush of a feather and a pinprick are perceived as distinct sensations because they are
detected by discrete cutaneous sensory neurons. Inflammation or nerve injury can disrupt …

Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …

Room temperature liquid metals (LMs) represent a class of emerging multifunctional
materials with attractive novel properties. Here, we show that photopolymerized LMs present …

Cutaneous neurogenic inflammation (CNI) is inflammation that is induced (or enhanced) in
the skin by the release of neuropeptides from sensory nerve endings. Clinical manifestations …

Optogenetics provides powerful means for precise control of neuronal activity; however, the
requirement of transgenesis and the incapability to extend the neuron excitation window into …

Transient receptor potential (TRP) channels are polymodal signal detectors that respond to
a wide range of physical and chemical stimuli. Elucidating how these channels integrate and …

Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

The ability to sense external temperature is assumed by somatosensory neurons, in which
temperature information is converted to neural activity by afferent input to the central nervous …

Nociception is the process whereby primary afferent nerve fibers of the somatosensory
system detect noxious stimuli. Pungent irritants from pepper, mint, and mustard plants have …

Tissue injury and inflammation markedly alter touch perception, making normally innocuous
sensations become intensely painful. Although this sensory distortion, known as tactile …