Whole genome sequencing contributions and challenges in disease reduction focused on malaria

OP Akoniyon, TS Adewumi, L Maharaj, OO Oyegoke… - Biology, 2022 - mdpi.com
Simple Summary Malaria is one of the most severe life-threatening human vector-borne
diseases worldwide today, leading to high mortality. Children under the age of five and …

Molecular markers for malaria genetic epidemiology: progress and pitfalls

S Ruybal-Pesántez, K McCann, J Vibin, S Siegel… - Trends in …, 2023 - cell.com
Over recent years, progress in molecular markers for genotyping malaria parasites has
enabled informative studies of epidemiology and transmission dynamics. Results have …

Inter-Population Genetic Diversity and Clustering of Merozoite Surface Protein-1 (pkmsp-1) of Plasmodium knowlesi Isolates from Malaysia and Thailand

NR Noordin, YL Lau, FW Cheong, MY Fong - Tropical Medicine and …, 2023 - mdpi.com
The genetic diversity of pkmsp-1 of Malaysian Plasmodium knowlesi isolates was studied
recently. However, the study only included three relatively older strains from Peninsular …

Genetic diversity of Plasmodium falciparum isolates in Nigeria. A review

AO Opute, JA Akinkunmi, AO Funsho… - Egyptian Journal of …, 2022 - Springer
Background The complexity of infection in malaria-endemic areas is exacerbated by the
presence of genetically diverse Plasmodium falciparum strains. There is a risk that more …

The diversity of Plasmodium falciparum isolates from asymptomatic and symptomatic school-age children in Kinshasa Province, Democratic Republic of Congo

SV Simpson, SS Nundu, H Arima, O Kaneko, T Mita… - Malaria Journal, 2023 - Springer
Abstract Background Understanding Plasmodium falciparum population diversity and
transmission dynamics provides information on the intensity of malaria transmission, which …

Plasmodium falciparum Merozoite Surface Proteins Polymorphisms and Treatment Outcomes among Patients with Uncomplicated Malaria in Mwanza, Tanzania

KJ Marwa, E Lyimo, ET Konje, A Kapesa… - Journal of Tropical …, 2022 - Wiley Online Library
Background. The severity of malaria infection depends on the host, parasite and
environmental factors. Merozoite surface protein (msp) diversity determines transmission …

Genomic approaches for monitoring transmission dynamics of malaria: A case for malaria molecular surveillance in Sub–Saharan Africa

BA Mensah, NE Akyea-Bobi, A Ghansah - Frontiers in Epidemiology, 2022 - frontiersin.org
Transmission dynamics is an important indicator for malaria control and elimination. As we
move closer to eliminating malaria in Sub-Saharan Africa (sSA), transmission indices with …

Prevalence of malaria and comparative diagnostic performance of malaria rapid diagnostic test against microscopy in Nasarawa-west senatorial District, Nasarawa …

IN Igbawua, YB Ngwai, D Ishaleku… - … Research and Reviews, 2024 - gsconlinepress.com
Malaria is a vector-borne parasitic disease caused by Plasmodium species, and transmitted
by the bite of an infected female anopheles mosquito. It remains a major public health …

Kelch 13 gene polymorphisms of Plasmodium falciparum among human population in Nasarawa-West Senatorial District, Nasarawa State, Nigeria

IN Igbawua, YB Ngwai - Open Access Research Journal of Science and …, 2024 - oarjst.com
Kelch-13 is a gene produced by Plasmodium falciparum, one of the species of Malaria
parasite. Malaria remains a major public health challenge especially in Sub-Saharan Africa …

[PDF][PDF] Amplicon Deep Sequencing Elucidates the Complexity of Infection in Pathogens of Global Health Importance

D Castañeda Mogollón - 2023 - prism.ucalgary.ca
The work included in this Ph. D. thesis was designed, generated, performed, and written by
Daniel Castañeda Mogollón at the University of Calgary in Calgary, Alberta, Canada. This …