Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans
Ageing is driven by a loss of transcriptional and protein homeostasis,, and is the key risk
factor for multiple chronic diseases. Interventions that attenuate or reverse systemic …
factor for multiple chronic diseases. Interventions that attenuate or reverse systemic …
[HTML][HTML] Structural and enzyme kinetic studies of retrograded starch: Inhibition of α-amylase and consequences for intestinal digestion of starch
Retrograded starch is known to be resistant to digestion. We used enzyme kinetic
experiments to examine how retrogradation of starch affects amylolysis catalysed by porcine …
experiments to examine how retrogradation of starch affects amylolysis catalysed by porcine …
[HTML][HTML] Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation
RN DuMez-Kornegay, LS Baker, AJ Morris… - Plos …, 2024 - journals.plos.org
The popularity of the ancient, probiotic-rich beverage Kombucha Tea (KT) has surged in part
due to its purported health benefits, which include protection against metabolic diseases; …
due to its purported health benefits, which include protection against metabolic diseases; …
Olfactory perception of food abundance regulates dietary restriction-mediated longevity via a brain-to-gut signal
The role of food nutrients in mediating the positive effect of dietary restriction (DR) on
longevity has been extensively characterized, but how non-nutrient food components …
longevity has been extensively characterized, but how non-nutrient food components …
AMPK‐mediated formation of stress granules is required for dietary restriction‐induced longevity in Caenorhabditis elegans
CT Kuo, GT You, YJ Jian, TS Chen, YC Siao… - Aging …, 2020 - Wiley Online Library
Stress granules (SGs) are nonmembranous organelles that are dynamically assembled and
disassembled in response to various stressors. Under stressed conditions, polyadenylated …
disassembled in response to various stressors. Under stressed conditions, polyadenylated …
[HTML][HTML] A gene-expression-based neural code for food abundance that modulates lifespan
How the nervous system internally represents environmental food availability is poorly
understood. Here, we show that quantitative information about food abundance is encoded …
understood. Here, we show that quantitative information about food abundance is encoded …
[HTML][HTML] Neuroprotective effects of dried camu-camu (Myrciaria dubia HBK McVaugh) residue in C. elegans
JCS Azevêdo, KC Borges, MI Genovese… - Food Research …, 2015 - Elsevier
The effect of hot air dried camu-camu (Myrciaria dubia HBK McVaugh) residue on
modulating redox response signaling was evaluated in transgenic Caenorhabditis elegans …
modulating redox response signaling was evaluated in transgenic Caenorhabditis elegans …
[HTML][HTML] The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans
CG Silva-García, LI Láscarez-Lagunas, K Papsdorf… - Nature Aging, 2023 - nature.com
Loss of function during aging is accompanied by transcriptional drift, altering gene
expression and contributing to a variety of age-related diseases. CREB-regulated …
expression and contributing to a variety of age-related diseases. CREB-regulated …
A micro RNA switch controls dietary restriction‐induced longevity through Wnt signaling
Y Xu, Z He, M Song, Y Zhou, Y Shen - EMBO reports, 2019 - embopress.org
Dietary restriction (DR) is known to have a potent and conserved longevity effect, yet its
underlying molecular mechanisms remain elusive. DR modulates signaling pathways in …
underlying molecular mechanisms remain elusive. DR modulates signaling pathways in …
[HTML][HTML] BLMP-1 is a critical temporal regulator of dietary-restriction-induced response in Caenorhabditis elegans
Q Hu, Y Xu, M Song, Y Dai, A Antebi, Y Shen - Cell Reports, 2024 - cell.com
The extrinsic diet and the intrinsic developmental programs are intertwined. Although
extensive research has been conducted on how nutrition regulates development, whether …
extensive research has been conducted on how nutrition regulates development, whether …