Early Breast Cancer Risk Assessment: Integrating Histopathology with Artificial Intelligence

M Ivanova, C Pescia, D Trapani, K Venetis… - Cancers, 2024 - mdpi.com
Simple Summary Risk assessment in early breast cancer is critical for clinical decisions, but
defining risk categories poses a significant challenge. The integration of conventional …

The Evolving Role of Genomic Testing in Early Breast Cancer: Implications for Diagnosis, Prognosis, and Therapy

K Venetis, C Pescia, G Cursano, C Frascarelli… - International Journal of …, 2024 - mdpi.com
Multigene prognostic genomic assays have become indispensable in managing early breast
cancer (EBC), offering crucial information for risk stratification and guiding adjuvant …

PIK3CA testing in hormone receptor-positive/HER2-negative metastatic breast cancer: real-world data from Italian molecular pathology laboratories

F Pepe, K Venetis, G Cursano, C Frascarelli… - …, 2024 - Taylor & Francis
Introduction: PIK3CA gene mutations occur in approximately 40% of hormone receptor-
positive/HER2-negative (HR+/HER2−) metastatic breast cancers (MBCs), electing them to …

Exploring habitats-based spatial distributions: improving predictions of lymphovascular invasion in invasive breast cancer

W Ge, X Fan, Y Zeng, X Yang, L Zhou, Z Zuo - Academic Radiology, 2024 - Elsevier
Rationale and Objectives Accurate assessment of lymphovascular invasion (LVI) in invasive
breast cancer (IBC) plays a pivotal role in tailoring personalized treatment plans. This study …

Navigating ethical challenges of integrating genomic medicine into clinical practice: Maximising beneficence in precision oncology

MJ Kotze, KA Grant, NC Van Der Merwe… - South African Journal …, 2024 - journals.co.za
The development of gene expression profiling and next-generation sequencing
technologies have steered oncogenomics to the forefront of precision medicine. This created …

[PDF][PDF] The Challenging Decision to Commence Neoadjuvant Chemotherapy for Hormone-Receptor-Positive Breast Cancer: NAC Hormone-positive Breast cancer

S Sadighi - Archives of Breast Cancer, 2024 - archbreastcancer.com
However, the idea that achieving a high pathological complete response (PCR) after
neoadjuvant chemotherapy serves as a reliable indicator for increased overall survival is …