[HTML][HTML] A critical review: recent advancements in the use of CRISPR/Cas9 technology to enhance crops and alleviate global food crises

A Rasheed, RA Gill, MU Hassan, A Mahmood… - Current Issues in …, 2021 - mdpi.com
Genome editing (GE) has revolutionized the biological sciences by creating a novel
approach for manipulating the genomes of living organisms. Many tools have been …

[HTML][HTML] CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope

V Karn, S Sandhya, W Hsu, D Parashar… - Cancer Cell …, 2022 - Springer
Cancer is one of the major causes of mortality worldwide, therefore it is considered a major
health concern. Breast cancer is the most frequent type of cancer which affects women on a …

A review on CRISPR/Cas-based epigenetic regulation in plants

P Jogam, D Sandhya, A Alok, V Peddaboina… - International Journal of …, 2022 - Elsevier
Epigenetic changes are the heritable modifications in genes without altering DNA
sequences. The epigenetic changes occur in the plant genomes to regulate gene …

[HTML][HTML] Seed dormancy and pre-harvest sprouting in rice—an updated overview

SI Sohn, S Pandian, TS Kumar… - International Journal of …, 2021 - mdpi.com
Pre-harvest sprouting is a critical phenomenon involving the germination of seeds in the
mother plant before harvest under relative humid conditions and reduced dormancy. As it …

[HTML][HTML] Hairy CRISPR: genome editing in plants using hairy root transformation

AS Kiryushkin, EL Ilina, ED Guseva, K Pawlowski… - Plants, 2021 - mdpi.com
CRISPR/Cas-mediated genome editing is a powerful tool of plant functional genomics. Hairy
root transformation is a rapid and convenient approach for obtaining transgenic roots. When …

[HTML][HTML] Genome editing for sustainable crop improvement and mitigation of biotic and abiotic stresses

MF Hamdan, CKS Karlson, EY Teoh, SE Lau, BC Tan - Plants, 2022 - mdpi.com
Climate change poses a serious threat to global agricultural activity and food production.
Plant genome editing technologies have been widely used to develop crop varieties with …

[HTML][HTML] Gene editing for plant resistance to abiotic factors: a systematic review

FS Nascimento, AJ Rocha, JMS Soares… - Plants, 2023 - mdpi.com
Agricultural crops are exposed to various abiotic stresses, such as salinity, water deficits,
temperature extremes, floods, radiation, and metal toxicity. To overcome these challenges …

[HTML][HTML] Green revolution to gene revolution: Technological advances in agriculture to feed the world

MF Hamdan, SN Mohd Noor, N Abd-Aziz, TL Pua… - Plants, 2022 - mdpi.com
Technological applications in agriculture have evolved substantially to increase crop yields
and quality to meet global food demand. Conventional techniques, such as seed saving …

[HTML][HTML] CRISPR/Cas9 landscape: Current state and future perspectives

M Tyumentseva, A Tyumentsev, V Akimkin - International Journal of …, 2023 - mdpi.com
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 is a unique
genome editing tool that can be easily used in a wide range of applications, including …

Overview of advances in CRISPR/deadCas9 technology and its applications in human diseases

MM Kanafi, M Tavallaei - Gene, 2022 - Elsevier
Prokaryotes possess an adaptive immune system using various CRISPR associated (Cas)
genes to make an archive of records from invading phages and eliminate them upon re …