Progresses in polymeric nanoparticles for delivery of tyrosine kinase inhibitors
Tyrosine kinase inhibitors (TKIs), as an important class of chemotherapeutic drugs, induce
apoptosis by altering the path of the cellular signal, resulting in cell death. However, some …
apoptosis by altering the path of the cellular signal, resulting in cell death. However, some …
Computational investigation of Moringa oleifera phytochemicals targeting EGFR: molecular docking, molecular dynamics simulation and density functional theory …
MA Yousaf, SA Anwer, S Basheera… - Journal of Biomolecular …, 2024 - Taylor & Francis
Epidermal growth factor receptor (EGFR) is a prominent target for anticancer therapy due to
its role in activating several cell signaling cascades. Clinically approved EGFR inhibitors are …
its role in activating several cell signaling cascades. Clinically approved EGFR inhibitors are …
LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer
D Tong, X Wang, L Liu, T Wen, QY Chen… - Cancer Gene …, 2023 - nature.com
The epidermal growth factor receptor (EGFR) is one of the first and most prominent driver
genes known to promote malignant lung cancer. Investigating regulatory mechanisms …
genes known to promote malignant lung cancer. Investigating regulatory mechanisms …
A non-enhancing, T2 fluid-attenuated inversion recovery hyperintense, diffusion-restricting brainstem lesion in an EGFR tyrosine kinase inhibitor-treated non-small …
CA Yuen, S Bao, XT Kong - Biomarkers in Medicine, 2024 - Taylor & Francis
Leptomeningeal metastasis (LM) is a devastating complication of malignancy. Diagnosis
relies on both contrast enhancement on imaging and malignant cells in cerebral spinal fluid …
relies on both contrast enhancement on imaging and malignant cells in cerebral spinal fluid …
[PDF][PDF] Concomitant EGFR Mutations and ALK Rearrangements in Lung Adenocarcinoma Treated With Osimertinib
D Thomas, MKE Maloney, G Raval - Cureus, 2023 - cureus.com
Lung cancer is the third most common cancer in addition to being the cancer responsible for
the most annual deaths in the United States, comprising 15% of all diagnosed cancers, and …
the most annual deaths in the United States, comprising 15% of all diagnosed cancers, and …
Prognostic significance, predictive value, and targeting of the HER-family members in pancreatic cancer
T Khan - 2023 - eprints.kingston.ac.uk
Pancreatic cancer is one of the most aggressive, heterogeneous, and deadliest types of
human cancer. In the past few decades, aberrant expression and activation of human …
human cancer. In the past few decades, aberrant expression and activation of human …
Plasma genomic biomarkers for New Zealand cancer patients
SJ Fitzgerald - 2021 - researchspace.auckland.ac.nz
With the increasing global focus on integrating circulating tumour DNA (ctDNA) analysis into
routine cancer care, this thesis describes research to develop and evaluate ctDNA analysis …
routine cancer care, this thesis describes research to develop and evaluate ctDNA analysis …