Although there is increasing clinical recognition of behavioral addictions, of which gambling
disorder is the prototype example, there is a limited understanding of the psychological …

The fronto-striatal circuitry, involving the nucleus accumbens, ventral tegmental area, and
prefrontal cortex, mediates goal-directed behavior and is targeted by both drugs of abuse …

Influential accounts of addiction posit alterations in adaptive behavior driven by deficient
dopaminergic prediction errors (PEs), signaling the discrepancy between actual and …

Rationale Drug addiction has been suggested to develop through drug-induced changes in
learning and memory processes. Whilst the initiation of drug use is typically goal-directed …

Background Drug-induced alterations to the dopamine system in stimulant use disorder
(SUD) are hypothesized to impair reinforcement learning (RL). Computational modeling …

Maladaptive behavior in drug addiction is widely regarded as a result of neurocognitive
dysfunctions. Recently, there has been a growing trend to adopt computational methods to …

Every day we are faced with a huge amount of new information. We can't learn about
everything, we have to select what to learn about. We have many systems that contribute to …

Certain memories resist extinction to continue invigorating maladaptive actions. The
robustness of these memories could depend on their widely distributed implementation …

Goal-directed behavior relies on accurate mental representations of the value of expected
outcomes. Disruptions to this process are a central feature of several neuropsychiatric …

Although maladaptive decision-making is a defining feature of drug abuse and addiction, we
have yet to ascertain how cocaine self-administration disrupts neural signals in anterior …