Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis

AOM Wilkie, JC Byren, JA Hurst, J Jayamohan… - …, 2010 - publications.aap.org
OBJECTIVES: We describe the first cohort-based analysis of the impact of genetic disorders
in craniosynostosis. We aimed to refine the understanding of prognoses and pathogenesis …

A review of the management of single-suture craniosynostosis, past, present, and future: JNSPG 75th Anniversary Invited Review Article

MR Proctor, JG Meara - Journal of Neurosurgery: Pediatrics, 2019 - thejns.org
BACKGROUND Craniosynostosis is a condition in which 2 or more of the skull bones fuse
prematurely. The spectrum of the disorder most commonly involves the closure of a single …

[HTML][HTML] Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis

L Ma, Q Chang, F Pei, M Liu, W Zhang, YK Hong… - Cell Stem Cell, 2023 - cell.com
The meninges lie in the interface between the skull and brain, harboring lymphatic
vasculature and skull progenitor cells (SPCs). How the skull and brain communicate …

[HTML][HTML] A genetic-pathophysiological framework for craniosynostosis

SRF Twigg, AOM Wilkie - The American Journal of Human Genetics, 2015 - cell.com
Craniosynostosis, the premature fusion of one or more cranial sutures of the skull, provides
a paradigm for investigating the interplay of genetic and environmental factors leading to …

[HTML][HTML] Skeletogenic fate of zebrafish cranial and trunk neural crest

E Kague, M Gallagher, S Burke, M Parsons… - PloS one, 2012 - journals.plos.org
The neural crest (NC) is a major contributor to the vertebrate craniofacial skeleton, detailed
in model organisms through embryological and genetic approaches, most notably in chick …

Cranial sutures: a brief review

BJ Slater, KA Lenton, MD Kwan… - Plastic and …, 2008 - journals.lww.com
Craniosynostosis, or the premature fusion of one or more cranial sutures, is a relatively
common congenital defect that causes a number of morphologic and functional …

[HTML][HTML] Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth

P Nieminen, NV Morgan, AL Fenwick… - The American Journal of …, 2011 - cell.com
Craniosynostosis and supernumerary teeth most often occur as isolated developmental
anomalies, but they are also separately manifested in several malformation syndromes …

[HTML][HTML] The intertwined evolution and development of sutures and cranial morphology

HE White, A Goswami, AS Tucker - Frontiers in Cell and …, 2021 - frontiersin.org
Phenotypic variation across mammals is extensive and reflects their ecological
diversification into a remarkable range of habitats on every continent and in every ocean …

Data science and data analytics: artificial intelligence and machine learning integrated based approach

S Chauhan, M Singh… - Data science and data …, 2021 - api.taylorfrancis.com
In the previous few decades, all companies have produced data in large amounts from
different sources. It can be from business applications of their own, social media or other …

[HTML][HTML] RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesity

D Jenkins, D Seelow, FS Jehee, CA Perlyn… - The American Journal of …, 2007 - cell.com
Carpenter syndrome is a pleiotropic disorder with autosomal recessive inheritance, the
cardinal features of which include craniosynostosis, polysyndactyly, obesity, and cardiac …