The emerging role of leukemia inhibitory factor in cancer and therapy
Leukemia inhibitory factor (LIF) is a multi-functional cytokine of the interleukin-6 (IL-6)
superfamily. Initially identified as a factor that inhibits the proliferation of murine myeloid …
superfamily. Initially identified as a factor that inhibits the proliferation of murine myeloid …
Leukemia inhibitory factor, a double-edged sword with therapeutic implications in human diseases
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine of the interleukin-6 (IL-6)
superfamily. LIF was initially discovered as a factor to induce the differentiation of myeloid …
superfamily. LIF was initially discovered as a factor to induce the differentiation of myeloid …
Leukemia inhibitory factor: an important cytokine in pathologies and cancer
MM Jorgensen, P de la Puente - Biomolecules, 2022 - mdpi.com
Leukemia Inhibitory Factor (LIF) is a member of the IL-6 cytokine family and is expressed in
almost every tissue type within the body. Although LIF was named for its ability to induce …
almost every tissue type within the body. Although LIF was named for its ability to induce …
[PDF][PDF] Emerging perspectives on leukemia inhibitory factor and its receptor in cancer
J Christianson, JT Oxford, CL Jorcyk - Frontiers in Oncology, 2021 - frontiersin.org
Tumorigenesis and metastasis have deep connections to inflammation and inflammatory
cytokines, but the mechanisms underlying these relationships are poorly understood …
cytokines, but the mechanisms underlying these relationships are poorly understood …
The regulation of cyclins and cyclin-dependent kinases in the development of gastric cancer
A Javed, M Yarmohammadi, KS Korkmaz… - International Journal of …, 2023 - mdpi.com
Gastric cancer predominantly occurs in adenocarcinoma form and is characterized by
uncontrolled growth and metastases of gastric epithelial cells. The growth of gastric cells is …
uncontrolled growth and metastases of gastric epithelial cells. The growth of gastric cells is …
The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights
The dysregulation of leukemia inhibitory factor (LIF) and its cognate receptor (LIFR) has
been associated with multiple cancer initiation, progression, and metastasis. LIF plays a …
been associated with multiple cancer initiation, progression, and metastasis. LIF plays a …
Leukaemia inhibitory factor (LIF) inhibits cancer stem cells tumorigenic properties through hippo kinases activation in gastric cancer
L Seeneevassen, J Giraud, S Molina-Castro, E Sifré… - Cancers, 2020 - mdpi.com
Cancer stem cells (CSCs) present chemo-resistance mechanisms contributing to tumour
maintenance and recurrence, making their targeting of utmost importance in gastric cancer …
maintenance and recurrence, making their targeting of utmost importance in gastric cancer …
[HTML][HTML] High expression of bone morphogenetic protein 1 (BMP1) is associated with a poor survival rate in human gastric cancer, a dataset approaches
Abstract Bone morphogenetic protein 1 (BMP1) is a secreted metalloprotease of the astacin
M12A family of bone morphogenetic proteins (BMPs). BMP1 activates transforming growth …
M12A family of bone morphogenetic proteins (BMPs). BMP1 activates transforming growth …
Tumor-derived LIF promotes chemoresistance via activating tumor-associated macrophages in gastric cancers
S Yu, Q Li, Y Wang, Y Cui, Y Yu, W Li, F Liu… - Experimental cell …, 2021 - Elsevier
Chemotherapy is the preferred clinical treatment for advanced stage gastric cancer (GC)
patients, of which efficacy could be markedly impaired due to the development of …
patients, of which efficacy could be markedly impaired due to the development of …
Role of PGRMC1 in cell physiology of cervical cancer
CC Shih, HC Chou, YJ Chen, WH Kuo, CH Chan… - Life sciences, 2019 - Elsevier
Aims The most frequent cancers among women worldwide. The mortality of cervical cancer
has declined significantly primarily due to the widespread use of Pap smear tests as a …
has declined significantly primarily due to the widespread use of Pap smear tests as a …