The good, the bad and the new about uric acid in cancer

S Allegrini, M Garcia-Gil, R Pesi, M Camici, MG Tozzi - Cancers, 2022 - mdpi.com
Simple Summary The concentration of uric acid in blood is sex-, age-and diet-dependent
and is maintained close to its maximal solubility, indicating that it plays some important role …

PAICS as a potential target for cancer therapy linking purine biosynthesis to cancer progression

A Huo, X Xiong - Life Sciences, 2023 - Elsevier
Tumor cells are required to undergo metabolic reprogramming for rapid development and
progression, and one of the metabolic characteristics of cancer cells is the excessive …

High serum uric acid may associate with the increased risk of colorectal cancer in females: a prospective cohort study

N Mi, J Huang, C Huang, Y Lin, Q He… - … journal of cancer, 2022 - Wiley Online Library
Elevated serum uric acid (SUA) levels have been previously reported to play a role in
multiple types of cancers. However, epidemiological studies evaluating SUA levels and …

Comprehensive analysis of purine-metabolism-related gene signature for predicting ovarian cancer prognosis, immune landscape, and potential treatment options

J Liu, X Zhang, H Wang, X Zuo, L Hong - Journal of Personalized …, 2023 - mdpi.com
Purine metabolism is an important branch of metabolic reprogramming and has received
increasing attention in cancer research. Ovarian cancer is an extremely dangerous …

Association between Gout and Gastric Cancer: A Nested Case–Control Study Using a National Health Sample Cohort

MJ Kwon, KM Han, JH Kim, JH Kim, MJ Kim… - Journal of Personalized …, 2024 - mdpi.com
Given the global significance of gout and gastric cancer (GC) as major health problems with
interrelated impacts, we examined the development of GC in Korean patients with gout. We …

J-shaped association between uric acid and breast cancer risk: a prospective case–control study

K Fan, T Sun, F Yin - Journal of Cancer Research and Clinical Oncology, 2023 - Springer
Background/aim In terms of breast cancer risk, there is no consensus on the effect of uric
acid (UA) levels. The aim of our study was to clarify the link between UA and breast cancer …

[HTML][HTML] Association between serum uric acid and colorectal cancer risk in European population: a two-sample Mendelian randomization study

J Zhou, R Fu, J Zhang, S Zhang, Z Lin, Z Lin… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Objectives This study aimed to explore the potential causal associations between serum uric
acid (SUA) and the risk of colorectal cancer, colon cancer and rectal cancer. Methods …

Clinical and biological data in patients with pancreatic cancer vs. chronic pancreatitis—A single center comparative analysis

G Gheorghe, VA Ionescu, H Moldovan, CC Diaconu - Diagnostics, 2023 - mdpi.com
Introduction: In some patients with chronic pancreatitis, the diagnosis of pancreatic cancer
can be missed. The objective of the study was to identify clinical and paraclinical data with …

Correlation between Serum Oxidative Stress Level and Serum Uric Acid and Prognosis in Patients with Hepatitis B‐Related Liver Cancer before Operation

M Yu, C Zhang, H Tang, C Xiao - Journal of Healthcare …, 2022 - Wiley Online Library
Aiming to explore the correlation between preoperative serum oxidative stress level and
serum uric acid and prognosis of hepatitis B‐related liver cancer, the clinical data of 712 …

Causal relationship between genetic-predicted uric acid and cervical cancer risk: evidence for nutritional intervention on cervical cancer prevention

C Cao, D Cai, H Liu, X Zhang, L Cai, C Sun… - Frontiers in …, 2024 - frontiersin.org
Introduction The relationship between serum uric acid (SUA) and cervical cancer is
inconclusive. This study aims to investigate the causal relationship between SUA levels and …