Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …

Monitoring of chemicals in the aquatic environment by chemical analysis alone cannot
completely assess and predict the effects of chemicals on aquatic species and ecosystems …

Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …

Thyroid hormone system disrupting compounds are considered potential threats for human
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …

A growing number of environmental pollutants are known to adversely affect the thyroid
hormone system, and major gaps have been identified in the tools available for the …

While chemical analysis of contaminant mixtures remains an essential component of
environmental monitoring, bioactivity-based assessments using in vitro systems increasingly …

ABSTRACT In 2007 the United States National Research Council (NRC) published a vision
for toxicity testing in the 21st century that emphasized the use of in vitro high‐throughput …

The increasing production, use and emission of synthetic chemicals into the environment
represents a major driver of global change. The large number of synthetic chemicals, limited …

Thyroid hormones (THs) are involved in the regulation of many important physiological and
developmental processes, including vertebrate eye development. Thyroid hormone system …