Dental, oral, and maxillofacial diseases are some of the most common problems in small
animal veterinary practice. These conditions create significant pain as well as localized and …

Multimodal approaches to pain management have arisen with the goal of improving
postoperative pain and reducing opioid analgesic use. We performed a comprehensive …

Methods A prospective study was conducted during the academic year September-
November 2017, randomly among 20 dental patients who visited the outpatient Department …

IMPLICATIONS: This meta-analysis assesses the ability of preemptive analgesic
interventions to attenuate postoperative pain scores, decrease supplemental postoperative …

NSAIDs inhibit the cyclo-oxygenase enzymes, and decrease peripheral and central
prostaglandin production. In addition to reducing the inflammation that accompanies tissue …

Preemptive analgesia means that an analgesic intervention is started before the noxious
stimulus arises in order to block peripheral and central nociception. This afferent blockade of …

Clinical evidence suggests that–besides their well known analgesic activity–opioids can
increase rather than decrease sensitivity to noxious stimuli. Based on the observation that …

Intractable neuropathic pain often results from nerve injury. One immediate event in
damaged nerve is a sustained increase in spontaneous afferent activity, which has a well …

Purpose The aim of the study was to investigate postoperative analgesia and the opioid-
sparing effect of the preoperative administration of intravenous flurbiprofen axetil in patients …

Purpose The current epidemic of prescription opioid abuse and misuse in the United States
is discussed, with an emphasis on the pharmacist's role in ensuring safe and effective opioid …