[HTML][HTML] Alveolar macrophages: Achilles' heel of SARS-CoV-2 infection

Z Wang, S Li, B Huang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused more than 6.3
million deaths to date. Despite great efforts to curb the spread of severe acute respiratory …

[HTML][HTML] Recapitulating infection, thermal sensitivity and antiviral treatment of seasonal coronaviruses in human airway organoids

P Li, Y Wang, MM Lamers, M Lavrijsen, C Iriondo… - …, 2022 - thelancet.com
Background Human seasonal coronaviruses usually cause mild upper-respiratory tract
infection, but severe complications can occur in specific populations. Research into …

[HTML][HTML] Microfluidic strategies for biomimetic lung chip establishment and SARS-CoV2 study

H Wang, T Wen, W Zhu, K Li, X Gong, Z Li - Materials Today Bio, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), characterized by its high
fatality rate and contagious nature, has led to significant morbidity and mortality worldwide …

Preparation and mechanism analysis of non-contact respiratory sensor based on ZnO/RGO composites

H Zhang, W Gu, C Chen - Applied Surface Science, 2022 - Elsevier
A humidity sensor based on zinc oxide (ZnO) and reduced graphene oxide (RGO)
composites (ZnO/RGO) for non-contact respiratory detection was fabricated by hydrothermal …

[HTML][HTML] Construction and application of in vitro alveolar models based on 3D printing technology

T Liu, C Zhou, Y Shao, Z Xiong, D Weng, Y Pang… - Chinese Journal of …, 2022 - Elsevier
Increasing lung diseases, mutating coronaviruses, and the development of new compounds
urgently require biomimetic in vitro lung models for lung pathology, toxicology, and …

[HTML][HTML] Emerging toolset of three-dimensional pulmonary cell culture models for simulating lung pathophysiology towards mechanistic elucidation and therapeutic …

K Ni, B Che, C Yang, Y Qin, R Gu, C Wang… - Frontiers in …, 2022 - frontiersin.org
The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) poses a never before seen challenge to human health and the …

Genome-engineering technologies for modeling and treatment of cystic fibrosis

M Dębczyński, D Mojsak, Ł Minarowski… - Advances in Medical …, 2023 - Elsevier
Cystic fibrosis (CF) is an autosomal recessive disease caused by defects in the CF
transmembrane conductance regulator (CFTR) protein. Due to the genetic nature of the …

Organoides de cérebro como modelos de doenças de Alzheimer e Parkinson: uma revisão narrativa sobre as perspectivas para medicina regenerativa e …

RTV de Souza, PHG Santana, RC Parreira… - Medicina (Ribeirão …, 2023 - revistas.usp.br
Há muitos anos a cultura celular bidimensional (2D) é utilizada como modelo de estudo de
doenças, possuindo grande importância na medicina regenerativa, apesar de ainda conter …

Utility of Lung Organoids to Accelerate Our Understanding of Human Pulmonary Development and Diseases

N Pek, M Gu - Lung Biology and Pathophysiology, 2024 - taylorfrancis.com
Organoids are intricate 3D conglomerations of self-organized cells that bear cellular and
structural resemblance to organs. Also coined" mini-organs," organoids are able to …

[PDF][PDF] Brain organoids as models of Alzheimer's and Parkinson's diseases: a narrative review on perspectives for regenerative and personalized medicine

RTV de Souza, PHG Santana, RC Parreira, LF Oliveira… - revistas.usp.br
1. Centro Universitário de Mineiros (UNIFIMES), Mineiros,(GO), Brasil. 2. Universidade
Federal do Triângulo Mineiro (UFTM), Uberaba,(MG), Brasil. 3. Universidade de São Paulo …