Congenital heart disease, particularly cyanotic congenital heart disease (CCHD), may lead
to a neurodevelopmental delay through central nervous system injury, more unstable central …

Background Circulatory vulnerability reflected by low systemic venous oxygen saturation
after surgical palliation of hypoplastic left heart syndrome predicts adverse neurologic …

Background Congenital heart disease (CHD) affects roughly 40,000 children annually.
Despite advancements, children undergoing surgery for CHD are at an increased risk for …

Purpose: The purpose of this study was to assess the extent of the increased intracranial
pressure (ICP) resulting from CO2 pneumoperitoneum and steep Trendelenburg positioning …

The potential role of systemic inflammation on brain injury in newborns with congenital heart
disease (CHD) was assessed by measuring levels of central nervous system (CNS)‑derived …

Background Measurement of cerebral venous oxyhemoglobin saturation (ScvO 2) is
considered a gold standard in assessing the adequacy of tissue oxygen delivery (DO 2) after …

Background Children with congenital heart disease are at increased risk of abnormal
neurodevelopment (ND). Demographic and perioperative physiologic factors have both …

Background Newborns with congenital heart disease have associated brain damage that
affects short-and long-term neurodevelopment. Several neuronal biomarkers exist that could …

Background In adults, xenon has only minimal hemodynamic side effects when compared
with other anesthetics. Moreover, in preclinical experiments, xenon has been demonstrated …

Although accumulating evidence has suggested that microRNAs (miRNAs) have a serious
impact on cognitive function and are associated with the etiology of several neuropsychiatric …