Keratinocyte differentiation is an essential process for epidermal stratification and stratum
corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start …

Severe trauma or chronic wounds can deplete the keratinocyte stem cells (KSCs) present in
the epidermal basal layer or inhibit their migration leading to compromised wound healing …

CacyBP/SIP is a multifunctional protein present in various cells and tissues. However, its
expression and role in the epidermis has not been explored so far. In this work, using RT …

CRISPR-Cas9 is the most straightforward genome-editing tool to date. However, its
implementation across disciplines is hampered by variable genome-editing efficiencies …

Aging progressively modifies the physiological balance of the organism increasing
susceptibility to both genetic and sporadic neurodegenerative diseases. These changes …

Epidermis is the outer skin layer built of specialized cells called keratinocytes. Keratinocytes
undergo a unique differentiation process, also known as cornification, during which their …

The epidermis is the outer part of the skin that protects the organism from dehydration and
shields from external insults. Epidermal cells, called keratinocytes, undergo a series of …

Objective: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility and
ultimately lethal blistering disease caused by mutations in the COL7A1 gene which is …

The epidermis is the outer part of the skin that protects the organism from dehydration and
shields from external insults. Epidermal cells, called keratinocytes, undergo a series of …