[HTML][HTML] Can local heating and molecular crowders disintegrate amyloid aggregates?

N Kumar, P Khatua, SK Sinha - Chemical Science, 2024 - pubs.rsc.org
The present study employs a blend of molecular dynamics simulations and a theoretical
model to explore the potential disintegration mechanism of a matured Aβ octamer, aiming to …

[HTML][HTML] Integrating In Vitro and In Silico Approaches to Gain Insight into the Mechanism of Amyloid Fibrillogenesis

MM Bilog - 2024 - academicworks.cuny.edu
Amyloid fibril formation, the hallmark of numerous amyloid-related diseases, has been the
subject of a vast number of scientific studies due to its pathological implications. Since the …