The fundamental mechanisms governing the perpetuation of atrial fibrillation (AF), the most
common arrhythmia seen in clinical practice, are poorly understood, which explains in part …

Diabetes mellitus (DM) represents one of the most important risk factors for atrial fibrillation
(AF) while AF is a strong and independent marker of overall mortality and cardiovascular …

Atrial fibrillation (AF), defined by disorganized atrial cardiac rhythm, is the most prevalent
cardiac arrhythmia worldwide. Recent genetic studies have highlighted a major heritable …

Transient receptor potential melastatin-7 (TRPM7) channels have been recently reported in
human atrial fibroblasts and are believed to mediate fibrogenesis in human atrial fibrillation …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in human beating
hearts. AF initiates self-perpetuating changes in electrophysiology, structure and functional …

Background—Genetic mechanisms of atrial fibrillation (AF) remain incompletely understood.
Previous differential expression studies in AF were limited by small sample size and …

The acetylcholine-activated inward rectifier potassium current (I KACh) is constitutively
active in persistent atrial fibrillation (AF). We tested the hypothesis that the blocking of I …

Oxidative stress has been implicated in the pathogenesis of atrial fibrillation. There are
multiple systems in the myocardium which contribute to redox homeostasis, and loss of …

Atrial fibrillation is the most common rhythm disturbance encountered in clinical practice.
Although often considered as solely arrhythmic in nature, current evidence has established …

The purpose of this study was to investigate whether atrial overexpression of angiotensin-
converting enzyme 2 (ACE2) by homogeneous transmural atrial gene transfer can reverse …