Recent advances in research on polyphenols: effects on microbiota, metabolism, and health

HN Rajha, A Paule, G Aragonès… - Molecular Nutrition & …, 2022 - Wiley Online Library
Polyphenols have attracted huge interest among researchers of various disciplines because
of their numerous biological activities, such as antioxidative, antiinflammatory, antiapoptotic …

[HTML][HTML] Role of hypoxia in cellular senescence

H Gao, E Nepovimova, Z Heger, M Valko, Q Wu… - Pharmacological …, 2023 - Elsevier
Senescent cells persist and continuously secrete proinflammatory and tissue-remodeling
molecules that poison surrounding cells, leading to various age-related diseases, including …

[HTML][HTML] Polyphenol-rich diet mediates interplay between macrophage-neutrophil and gut microbiota to alleviate intestinal inflammation

D Han, Y Wu, D Lu, J Pang, J Hu, X Zhang… - Cell death & …, 2023 - nature.com
Dietary phenolic acids alleviate intestinal inflammation through altering gut microbiota
composition and regulating macrophage activation. However, it is unclear how individual …

[HTML][HTML] Bacteroides fragilis restricts colitis-associated cancer via negative regulation of the NLRP3 axis

X Shao, S Sun, Y Zhou, H Wang, Y Yu, T Hu, Y Yao… - Cancer letters, 2021 - Elsevier
Patients with persistent ulcerative colitis (UC) are at a higher risk of developing colitis-
associated cancer (CAC). Previous studies have reported that intestinal microbiota …

[Retracted] Dietary Quercetin Supplementation Attenuates Diarrhea and Intestinal Damage by Regulating Gut Microbiota in Weanling Piglets

B Xu, W Qin, Y Xu, W Yang, Y Chen… - Oxidative medicine …, 2021 - Wiley Online Library
Antioxidant polyphenols from plants are potential dietary supplementation to alleviate early
weaning‐induced intestinal disorders in piglets. Recent evidences showed polyphenol …

[HTML][HTML] Ginsenoside Rg1 ameliorated experimental colitis by regulating the balance of M1/M2 macrophage polarization and the homeostasis of intestinal flora

J Long, XK Liu, ZP Kang, MX Wang, HM Zhao… - European Journal of …, 2022 - Elsevier
Aberrant M1/M2 macrophage polarization and dysbiosis are involved in the pathogenesis of
ulcerative colitis (UC). Ginsenoside Rg1 exhibits optimal immunomodulatory and anti …

Vitamin E alpha-and gamma-tocopherol mitigate colitis, protect intestinal barrier function and modulate the gut microbiota in mice

KY Liu, CH Nakatsu, Y Jones-Hall, A Kozik… - Free Radical Biology and …, 2021 - Elsevier
Inflammatory bowel diseases (IBDs) including colitis are intestinal disorders characterized
by chronic inflammation, barrier dysfunction and dysbiosis. Specific forms of vitamin E have …

[HTML][HTML] Eucommia ulmoides polysaccharide modified nano-selenium effectively alleviated DSS-induced colitis through enhancing intestinal mucosal barrier function …

R Ye, Q Guo, J Huang, Z Wang, Y Chen… - Journal of …, 2023 - Springer
Ulcerative colitis (UC) is currently the most common inflammatory bowel disease (IBD). Due
to its diverse and complex causes, there is no cure at present, and researchers are …

Integrated analysis of colorectal cancer reveals cross-cohort gut microbial signatures and associated serum metabolites

R Gao, C Wu, Y Zhu, C Kong, Y Zhu, Y Gao, X Zhang… - Gastroenterology, 2022 - Elsevier
Background & Aims Studies have reported abnormal gut microbiota or circulating
metabolome associated with colorectal cancer (CRC), but it remains a challenge to capture …

H2S‐Releasing Versatile Montmorillonite Nanoformulation Trilogically Renovates the Gut Microenvironment for Inflammatory Bowel Disease Modulation

T Jin, H Lu, Q Zhou, D Chen, Y Zeng, J Shi… - Advanced …, 2024 - Wiley Online Library
Abnormal activation of the intestinal mucosal immune system, resulting from damage to the
intestinal mucosal barrier and extensive invasion by pathogens, contributes to the …