Sarcopenic obesity is defined as a multifactorial disease in aging with decreased body
muscle, decreased muscle strength, decreased independence, increased fat mass, due to …

Consumption of a high calorie diet with irregular eating and sedentary behavior habits is
typical of the current suboptimal lifestyle, contributing to the development of metabolic …

Obesity is a metabolic disease that is caused by a lack of physical activity and is associated
with an increased risk of chronic inflammation. A total of 40 obese adolescent females with …

Disruption of leptin (LEP) signaling in the hypothalamus caused by type 2 diabetes (T2D)
can impair appetite regulation. The aim of this study was to investigate whether the …

Leptin is a tonic appetite-regulating hormone, which is integral for the long-term regulation of
energy balance. The current evidence suggests that the typical orexigenic or anorexigenic …

With the prevalence of obesity and associated comorbidities, studies aimed at revealing
mechanisms that regulate energy homeostasis have gained increasing interest. In 1994, the …

Obesity may cause metabolic syndrome and has become a global public health problem,
and dietary fibers (DF) could alleviate obesity and metabolic syndrome by regulating …

Astrocytes and microglia play important roles in organizing the structure and function of
neuronal networks in the central nervous system (CNS). The dorsal diencephalic connection …

Our previous studies found that safflower yellow (SY) and its main component hydroxysafflor
yellow A (HSYA) could alleviate obesity and improve leptin resistance in high-fat diet (HFD) …

Exosome release varies depending on the physiological state of the cell, so they could play
a fundamental role in obesity, the biggest pandemic in today's societies. The beneficial …