Advances in bladder cancer biology and therapy

L Tran, JF Xiao, N Agarwal, JE Duex… - Nature Reviews …, 2021 - nature.com
The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …

Diagnosis and treatment of non-muscle invasive bladder cancer: AUA/SUO guideline

SS Chang, SA Boorjian, R Chou, PE Clark… - The Journal of …, 2016 - auajournals.org
Purpose: Although associated with an overall favorable survival rate, the heterogeneity of
non-muscle invasive bladder cancer (NMIBC) affects patients' rates of recurrence and …

Circ HIPK 3 sponges miR‐558 to suppress heparanase expression in bladder cancer cells

Y Li, F Zheng, X Xiao, F Xie, D Tao, C Huang, D Liu… - EMBO …, 2017 - embopress.org
Increasing evidences suggest that circular RNA s (circ RNA s) exert crucial functions in
regulating gene expression. In this study, we perform RNA‐seq and identify 6,154 distinct …

Updated 2016 EAU guidelines on muscle-invasive and metastatic bladder cancer

JA Witjes, T Lebret, EM Compérat, NC Cowan… - European urology, 2017 - Elsevier
Context Invasive bladder cancer is a frequently occurring disease with a high mortality rate
despite optimal treatment. The European Association of Urology (EAU) Muscle-invasive and …

CircRNA-ST6GALNAC6 increases the sensitivity of bladder cancer cells to erastin-induced ferroptosis by regulating the HSPB1/P38 axis

L Wang, S Wu, H He, K Ai, R Xu, L Zhang… - Laboratory …, 2022 - nature.com
Previous studies have demonstrated that circST6GALNAC6 is a tumor suppressor in bladder
cancer. However, the role of circST6GALNAC6 in ferroptosis remains unclear. In the current …

An EMT‐related gene signature for the prognosis of human bladder cancer

R Cao, L Yuan, B Ma, G Wang, W Qiu… - Journal of cellular and …, 2020 - Wiley Online Library
The transition from non–muscle‐invasive bladder cancer (NMIBC) to muscle‐invasive
bladder cancer (MIBC) is detrimental to bladder cancer (BLCA) patients. Here, we aimed to …

[HTML][HTML] A review on the evolution of PD-1/PD-L1 immunotherapy for bladder cancer: the future is now

J Bellmunt, T Powles, NJ Vogelzang - Cancer treatment reviews, 2017 - Elsevier
The treatment of bladder cancer has evolved over time to encompass not only the traditional
modalities of chemotherapy and surgery, but has been particularly impacted by the use of …

Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis

W Dong, J Bi, H Liu, D Yan, Q He, Q Zhou, Q Wang… - Molecular cancer, 2019 - Springer
Abstract Background Circular RNAs (circRNAs) have been considered to mediate
occurrence and development of human cancers, generally acting as microRNA (miRNA) …

Progress on Ras/MAPK signaling research and targeting in blood and solid cancers

M Dillon, A Lopez, E Lin, D Sales, R Perets, P Jain - Cancers, 2021 - mdpi.com
Simple Summary The Ras-Raf-MEK-ERK signaling pathway is responsible for regulating
cell proliferation, differentiation, and survival. Overexpression and overactivation of …

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

H Liu, J Bi, W Dong, M Yang, J Shi, N Jiang, T Lin… - Molecular Cancer, 2018 - Springer
Background Increasing evidence has revealed that circular RNAs (circRNAs) play crucial
roles in cancer biology. However, the role and underlying regulatory mechanisms of …