Targeted therapies in bladder cancer: an overview of in vivo research

KEM Van Kessel, TCM Zuiverloon, AR Alberts… - Nature reviews …, 2015 - nature.com
Survival of patients with muscle-invasive bladder cancer is poor and new therapies are
needed. Currently, none of the targeted agents that are approved for cancer therapy have …

Trends in the incidence and mortality of transitional cell carcinoma of the bladder for the last four decades in the USA: a SEER-based analysis

MJ Al-Husseini, A Kunbaz, AM Saad, JV Santos… - BMC cancer, 2019 - Springer
Background Transitional cell carcinoma (TCC) accounts for around 95% of bladder cancers
and is the 4th most common cancer among men and the tenth most common in women, in …

NF-κB inhibitor, BAY11-7082, suppresses M2 tumor-associated macrophage induced EMT potential via miR-30a/NF-κB/Snail signaling in bladder cancer cells

Q Zhang, Z Mao, J Sun - Gene, 2019 - Elsevier
Background Chronic inflammatory microenvironment has been shown to play a key role in
initiating tumorigenesis and facilitating malignant progression. Primary tumors surrounded …

Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway

J Liu, Y Zhang, C Yu, P Zhang, S Gu… - Drug Development …, 2021 - Wiley Online Library
Bladder cancer is one of the most common malignant tumors in the urinary system with high
mortality and morbidity. Evidence revealed that bergenin could affect the development of …

Diagnosis and staging of bladder cancer

M Sun, QD Trinh - Hematology/Oncology Clinics, 2015 - hemonc.theclinics.com
The current recommendations do not support routine bladder cancer (BCa) screening
because of insufficient evidence and lack of understanding of the effects of screening in the …

[HTML][HTML] Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway

L Wang, R Song, M Ma, Y Chen, Y Jiang, J Li… - Chemico-Biological …, 2023 - Elsevier
Bladder cancer is among the ten most prevalent cancer types worldwide, and its prognosis
has not improved significantly in the past three decades because of cognitive limitations in …

Updates on the use of intravesical therapies for non-muscle invasive bladder cancer: how, when and what

CC Peyton, J Chipollini, M Azizi, AM Kamat… - World journal of …, 2019 - Springer
Introduction Intravesical therapy has been an important aspect of the management of non-
muscle invasive bladder cancer (NMIBC) for 40 years. Bacillus Calmette–Guerin (BCG) is …

[PDF][PDF] MicroRNAs in urine supernatant as potential non-invasive markers for bladder cancer detection

T Hanus, J Mares, M Korabecna, M Babjuk - Neoplasma, 2016 - researchgate.net
Urinary bladder carcinoma contributes to 4% of newly diagnosed oncological diseases in
the Czech Republic. Biomarkers for its early non-invasive detection are therefore highly …

High-throughput sequencing identified circular RNA circUBE2K mediating RhoA associated bladder cancer phenotype via regulation of miR-516b-5p/ARHGAP5 axis

C Yang, Z Mou, S Wu, Y Ou, Z Zhang, X Chen… - Cell Death & …, 2021 - nature.com
Bladder cancer (BC) is known as a common and lethal urinary malignancy worldwide.
Circular RNAs (circRNAs), an emerging non-coding RNA, participate in carcinogenesis …

Identification of the functions and prognostic values of RNA binding proteins in bladder cancer

Y Wu, Z Liu, X Wei, H Feng, B Hu, B Liu, Y Luan… - Frontiers in …, 2021 - frontiersin.org
Post-transcriptional regulation plays a leading role in gene regulation and RNA binding
proteins (RBPs) are the most important posttranscriptional regulatory protein. RBPs had …