Taming transposable elements in vertebrates: from epigenetic silencing to domestication

MV Almeida, G Vernaz, ALK Putman, EA Miska - Trends in genetics, 2022 - cell.com
Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …

Transgenerational epigenetic inheritance: prevalence, mechanisms, and implications for the study of heredity and evolution

E Jablonka, G Raz - The Quarterly review of biology, 2009 - journals.uchicago.edu
This review describes new developments in the study of transgenerational epigenetic
inheritance, a component of epigenetics. We start by examining the basic concepts of the …

RepeatModeler2 for automated genomic discovery of transposable element families

JM Flynn, R Hubley, C Goubert… - Proceedings of the …, 2020 - National Acad Sciences
The accelerating pace of genome sequencing throughout the tree of life is driving the need
for improved unsupervised annotation of genome components such as transposable …

How does epigenetics influence the course of evolution?

A Ashe, V Colot, BP Oldroyd - … transactions of the …, 2021 - royalsocietypublishing.org
Epigenetics is the study of changes in gene activity that can be transmitted through cell
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …

DNA methylation patterns and epigenetic memory

A Bird - Genes & development, 2002 - genesdev.cshlp.org
The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …

[HTML][HTML] DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

M Okano, DW Bell, DA Haber, E Li - Cell, 1999 - cell.com
The establishment of DNA methylation patterns requires de novo methylation that occurs
predominantly during early development and gametogenesis in mice. Here we demonstrate …

H3K27 methylation: a promiscuous repressive chromatin mark

ET Wiles, EU Selker - Current opinion in genetics & development, 2017 - Elsevier
Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the
methylation of lysine 27 on histone H3 (H3K27me). This histone modification is a feature of …

The honey bee epigenomes: differential methylation of brain DNA in queens and workers

F Lyko, S Foret, R Kucharski, S Wolf… - PLoS …, 2010 - journals.plos.org
In honey bees (Apis mellifera) the behaviorally and reproductively distinct queen and worker
female castes derive from the same genome as a result of differential intake of royal jelly and …

Regulation and function of DNA methylation in plants and animals

XJ He, T Chen, JK Zhu - Cell research, 2011 - nature.com
DNA methylation is an important epigenetic mark involved in diverse biological processes.
In plants, DNA methylation can be established through the RNA-directed DNA methylation …

[HTML][HTML] Methylation-induced repression—belts, braces, and chromatin

AP Bird, AP Wolffe - Cell, 1999 - cell.com
). It may also contribute to immobilization of mammalian transposons, suppression of
transcriptional noise, and the control of tissue-specific gene expression, but decisive …