DNA methylation and epigenetic inheritance in plants and filamentous fungi

RA Martienssen, V Colot - Science, 2001 - science.org
Plants and filamentous fungi share with mammals enzymes responsible for DNA
methylation. In these organisms, DNA methylation is associated with gene silencing and …

Engineered nucleic acids and methods of use thereof

S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …

In vivo production of proteins

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

T Chakraborty, A De Fougerolles - US Patent 9,303,079, 2016 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

The methyl-CpG binding domain and the evolving role of DNA methylation in animals

B Hendrich, S Tweedie - TRENDS in Genetics, 2003 - cell.com
DNA methylation occurs in bacteria, fungi, plants and animals, however its role varies widely
among different organisms. Even within animal genomes, methylation patterns vary …

Polyploidy in fungi: evolution after whole-genome duplication

W Albertin, P Marullo - … of the Royal Society B: Biological …, 2012 - royalsocietypublishing.org
Polyploidy is a major evolutionary process in eukaryotes—particularly in plants and, to a
less extent, in animals, wherein several past and recent whole-genome duplication events …

The evolution of invertebrate gene body methylation

S Sarda, J Zeng, BG Hunt, SV Yi - Molecular biology and …, 2012 - academic.oup.com
DNA methylation of transcription units (gene bodies) occurs in the genomes of many animal
and plant species. Phylogenetic persistence of gene body methylation implies biological …

Arabidopsis cmt3 chromomethylase mutations block non-CG methylation and silencing of an endogenous gene

L Bartee, F Malagnac, J Bender - Genes & development, 2001 - genesdev.cshlp.org
Plants maintain cytosine methylation at CG and non-CG residues to control gene expression
and genome stability. In a screen for Arabidopsis mutants that alter methylation and …

Structure and function of eukaryotic DNA methyltransferases

T Chen, E Li - Current topics in developmental biology, 2004 - Elsevier
DNA methylation is a common epigenetic modification found in eukaryotic organisms
ranging from fungi to mammals. Over the past 15 years, a number of eukaryotic DNA …

[HTML][HTML] Interplay between two epigenetic marks: DNA methylation and histone H3 lysine 9 methylation

LM Johnson, X Cao, SE Jacobsen - Current Biology, 2002 - cell.com
Background: The heterochromatin of many eukaryotes is marked by both DNA methylation
and histone H3 lysine 9 (H3-K9) methylation, though the exact relationship between these …