Compositions and methods of altering cholesterol levels
SG Hoge, A De Fougerolles, JL Ellsworth - US Patent 8,980,864, 2015 - Google Patents
2014-03-21 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases
T Morales-Ruiz, AP Ortega-Galisteo… - Proceedings of the …, 2006 - National Acad Sciences
Cytosine methylation is an epigenetic mark that promotes gene silencing and plays
important roles in development and genome defense against transposons. Methylation …
important roles in development and genome defense against transposons. Methylation …
Epigenetic mechanisms and cancer: an interface between the environment and the genome
Z Herceg, T Vaissière - Epigenetics, 2011 - Taylor & Francis
Although epidemiological studies support the role of environment in a wide range of human
cancers, the precise mechanisms by which environmental exposures promote cancer …
cancers, the precise mechanisms by which environmental exposures promote cancer …
tRNomics: analysis of tRNA genes from 50 genomes of Eukarya, Archaea, and Bacteria reveals anticodon-sparing strategies and domain-specific features
C Marck, H Grosjean - Rna, 2002 - cambridge.org
From 50 genomes of the three domains of life (7 eukarya, 13 archaea, and 30 bacteria), we
extracted, analyzed, and compared over 4,000 sequences corresponding to cytoplasmic …
extracted, analyzed, and compared over 4,000 sequences corresponding to cytoplasmic …
Delivery and formulation of engineered nucleic acids
A De Fougerolles, SM Elbashir - US Patent 9,533,047, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
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Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders
T Chakraborty, A De Fougerolles - US Patent 9,220,755, 2015 - Google Patents
2014-02-21 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
DNA methylation, chromatin inheritance, and cancer
Cancer is a process driven by the accumulation of abnormalities in gene function. While
many of these changes are genetic, epigenetically mediated changes in gene expression …
many of these changes are genetic, epigenetically mediated changes in gene expression …
Codon usage and tRNA genes in eukaryotes: correlation of codon usage diversity with translation efficiency and with CG-dinucleotide usage as assessed by …
S Kanaya, Y Yamada, M Kinouchi, Y Kudo… - Journal of molecular …, 2001 - Springer
The species-specific diversity of codon usage in five eukaryotes (Schizosaccharomyces
pombe, Caenorhabditis elegans, Drosophila melanogaster, Xenopus laevis, and Homo …
pombe, Caenorhabditis elegans, Drosophila melanogaster, Xenopus laevis, and Homo …
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
45893552&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
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Arabidopsis DEMETER-LIKE proteins DML2 and DML3 are required for appropriate distribution of DNA methylation marks
AP Ortega-Galisteo, T Morales-Ruiz, RR Ariza… - Plant molecular …, 2008 - Springer
Cytosine DNA methylation is a stable epigenetic mark for maintenance of gene silencing
across cellular divisions, but it is a reversible modification. Genetic and biochemical studies …
across cellular divisions, but it is a reversible modification. Genetic and biochemical studies …