Acute Coronary Syndromes (ACS)—Unravelling Biology to Identify New Therapies—The Microcirculation as a Frontier for New Therapies in ACS

K Vaidya, B Tucker, S Patel, MKC Ng - Cells, 2021 - mdpi.com
In acute coronary syndrome (ACS) patients, restoring epicardial culprit vessel patency and
flow with percutaneous coronary intervention or coronary artery bypass grafting has been …

Impact of bivalirudin on ischemia/reperfusion injury in patients with reperfused STEMI assessed by cardiac magnetic resonance

Y Zhang, Z Zou, B Xu, B Chen, H Ge, S Ding, J Pu - Pharmaceuticals, 2024 - mdpi.com
Thrombin is an important ischemia/reperfusion injury (IRI) mediator in patients with ST-
elevation myocardial infarction (STEMI). This study examines the use of bivalirudin, a direct …

[HTML][HTML] Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion

ZY Gary, T Ramasamy, M Fazzari, X Chen… - …, 2022 - ncbi.nlm.nih.gov
Rationale: The treatment of microvascular obstruction (MVO) using ultrasound-targeted LNP
cavitation (UTC) therapy mechanically relieves the physical obstruction in the …

CMR in the diagnosis of ischemic heart disease

V Buffa, P Di Renzi - La radiologia medica, 2020 - Springer
Cardiovascular magnetic resonance has always been more often used in the last 10 years
in evaluation of heart disease. Role in diagnosis of ischemia and in evaluation of myocardial …

Clinical outcomes associated with various microvascular injury patterns identified by CMR after STEMI

I Lechner, M Reindl, T Stiermaier, C Tiller… - Journal of the American …, 2024 - jacc.org
Background The prognostic significance of various microvascular injury (MVI) patterns after
ST-segment elevation myocardial infarction (STEMI) is not well known. Objectives This study …

Chinese Medicine Shensong Yangxin Capsule (参松养心胶囊) Ameliorates Myocardial Microcirculation Dysfunction in Rabbits with Chronic Myocardial Infarction

C Jiang, X Wang, S Dang, X Wang, Q Deng… - Chinese journal of …, 2021 - Springer
Objective To investigate the effect of Chinese compound Shensong Yangxin Capsule
(参松养心胶囊, SSYX) on myocardial microcirculation in myocardial-infarcted rabbits …

Contrast-enhanced cardiac MRI is superior to non-contrast mapping to predict left ventricular remodeling at 6 months after acute myocardial infarction

H Chen, J Erley, K Muellerleile, D Saering… - European …, 2024 - Springer
Objectives Parametric mapping constitutes a novel cardiac magnetic resonance (CMR)
technique enabling quantitative assessment of pathologic alterations of left ventricular (LV) …

[HTML][HTML] Impact of intramyocardial hemorrhage on clinical outcomes in ST-elevation myocardial infarction: a systematic review and meta-analysis

R Vyas, KH Changal, S Bhuta, V Pasadyn… - Journal of the Society for …, 2022 - Elsevier
Background Intramyocardial hemorrhage (IMH) occurs after ST-elevation myocardial
infarction (STEMI) and has been documented using cardiac magnetic resonance imaging …

T2* mapping techniques: iron overload assessment and other potential clinical applications

K Menacho, A Abdel-Gadir, JC Moon… - Magnetic Resonance …, 2019 - mri.theclinics.com
Multiparametric mapping of the myocardium has become an area of great interest in the
recent year with multiple review articles and recommendation statements. 1 Despite most of …

Theranostic contribution of extracellular matrix metalloprotease inducer-paramagnetic nanoparticles against acute myocardial infarction in a pig model of coronary …

R Ramirez-Carracedo, M Sanmartin, A Ten… - Circulation …, 2022 - Am Heart Assoc
Background: Rapid screening and accurate diagnosis of acute myocardial infarction are
critical to reduce the progression of myocardial necrosis, in which proteolytic degradation of …