Innate immune cells play essential roles in modulating both immune defense and
inflammation by expressing a diverse array of cytokines and inflammatory mediators …

While inflammation induced by Toll-like receptor (TLR) signaling is required to combat
infection, persistent inflammation can damage host tissues and contribute to a myriad of …

Alterations of histone deacetylases (HDACs) have been found in various types of cancers
[1]. Among HDAC family members, HDAC6 is the only HDAC that possesses two functional …

The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …

Colorectal cancer (CRC) continues to be a major contributor to cancer-related mortality.
Connexin 40 (CX40) is one of the major gap junction proteins with the capacity in regulating …

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are emerging as a crucially important
protein family in tumors. However, it is unclear which family members are essential for …

RNA-binding proteins (RBPs) are a class of proteins that primarily function by interacting
with different types of RNAs and play a critical role in regulating the transcription and …

Phosphorylation is a major post-translation modification (PTM) of proteins which is finely
tuned by the activity of several hundred kinases and phosphatases. It controls most if not all …

Food allergy is widely recognized as a significant health issue, having escalated into a
global epidemic, subsequently giving rise to the development of numerous additional …

In the last few years, the sudden outbreak of COVID-19 caused by SARS-CoV-2 proved the
crucial importance of understanding how emerging viruses work and proliferate, in order to …