[HTML][HTML] Current landscape of preoperative neoadjuvant therapies for initial resectable colorectal cancer liver metastasis

XF Cheng, F Zhao, D Chen, FL Liu - World Journal of …, 2024 - ncbi.nlm.nih.gov
Colorectal cancer liver metastasis (CRLM) presents a clinical challenge, and optimizing
treatment strategies is crucial for improving patient outcomes. Surgical resection, a key …

[HTML][HTML] Response to preoperative chemotherapy: impact of change in total burden score and mutational tumor status on prognosis of patients undergoing resection …

A Ruzzenente, F Bagante, F Ratti, EW Beal… - Hpb, 2019 - Elsevier
Background Progression of colorectal liver metastasis (CRLM) on preoperative
chemotherapy has been associated with a worse prognosis compared with patients who …

External validation of two established clinical risk scores predicting outcome after local treatment of colorectal liver metastases in a nationwide cohort

K Bolhuis, GE Wensink, MAG Elferink, MJG Bond… - Cancers, 2022 - mdpi.com
Simple Summary Patients with colorectal liver metastases (CRLM) are able to achieve long-
term survival when they receive local treatment of CRLM (resection or tumor ablation) …

KRAS mutations are influential in driving hepatic metastases and predicting outcome in colorectal cancer

CW Steele, T Whittle, JJ Smith - Chinese Clinical Oncology, 2019 - cco.amegroups.org
Metastatic colorectal cancer (CRC) is a topic of intense research. KRAS mutations have
emerged as aggressive drivers of disease. Here we discuss the role of KRAS mutations in …

Reevaluating the prognostic value of ras mutation status in patients with resected liver metastases from colorectal cancer: A systematic review and meta‐analysis

E Pikoulis, D Papaconstantinou… - Journal of Hepato …, 2021 - Wiley Online Library
Background Although the value of Rat Sarcoma Oncogene (RAS) mutation status in
predicting long‐term outcomes in patients with colorectal liver metastases (CRLM) is widely …

[HTML][HTML] Prediction of survival in patients with colorectal liver metastases-development and validation of a prognostic score model

C Villard, A Abdelrafee, M Habib, N Ndegwa… - European Journal of …, 2022 - Elsevier
Background Metastatic spread of colorectal cancer to the liver impacts prognosis. Advances
in chemotherapy have resulted in increased resectability rates and thereby improved …

[HTML][HTML] Nomograms incorporating preoperative RDW level for the prediction of postoperative complications and survival in colorectal liver metastases after resection

Q Chen, R Mao, J Zhao, X Bi, Z Li… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: This study aimed to investigate the predictive significance of preoperative red
cell volume distribution width (RDW) level for prognosis and to establish nomograms …

Machine learning-based radiomics analysis in predicting RAS mutational status using magnetic resonance imaging

V Granata, R Fusco, MC Brunese, A Di Mauro… - La radiologia …, 2024 - Springer
Purpose To assess the efficacy of radiomics features, obtained by magnetic resonance
imaging (MRI) with hepatospecific contrast agent, in pre-surgical setting, to predict RAS …

[HTML][HTML] Molecular profiling and patient selection for the multimodal approaches for patients with resectable colorectal liver metastases

RLC Araujo, LG Fonseca, RO Silva… - … Surgery and Nutrition, 2024 - ncbi.nlm.nih.gov
Colorectal cancer represents the third most common cancer and about 20% are diagnosed
with synchronous metastatic disease. From a historical point of view, surgery remains the …

[HTML][HTML] Colorectal cancer liver metastases: an update of treatment strategy and future perspectives

D Hu, Y Pan, G Chen - Surgery in Practice and Science, 2021 - Elsevier
Introduction More than half of the colorectal cancer patients develop liver metastases in the
disease course, affecting at least 900,000 people worldwide each year. Regarding this …