Recent advances in vitamin D research indicate that this vitamin, a secosteroid hormone,
has beneficial effects on several body systems other than the musculoskeletal system. Both …

A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

We report the immediate effects of estrogen signaling on the transcriptome of breast cancer
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …

In the past, interactions between drugs and vitamin D have received only little or no attention
in the health care practices. However, since more and more drugs are used for the treatment …

Lipid rafts are sphingolipid‐and cholesterol‐rich domains of the plasma membrane which
contain a variety of signalling and transport proteins. Different subtypes of lipid rafts can be …

Vitamin D3 (cholecalciferol) is a secosteroid and prohormone which is metabolized in
various tissues to the biologically most active vitamin D hormone 1, 25 (OH) 2D3 (calcitriol) …

BACKGROUNDS & AIMS: Under normal conditions, the biliary tract is a microbial-free
environment. The absence of microorganisms has been attributed to various defense …

In addition to its role in calcium homeostasis and bone health, vitamin D has also been
reported to have anticancer activities against many cancer types, including breast cancer …

While the physiology of membrane-initiated estradiol signaling in the nervous system has
remained elusive, a great deal of progress has been made toward understanding the …

Purpose: Our previous work has shown low serum 25-hydroxyvitamin D concentrations in
association with aggressive breast cancer subtypes. Vitamin D receptor (VDR) is central for …