Aim Opioid use disorder (OUD) is a leading cause of preventable mortality amongst young
people worldwide. Early identification and intervention of modifiable risk factors may reduce …

Background Observational studies have found Attention Deficit Hyperactivity Disorder
(ADHD) to be associated with an increased risk of adverse outcomes as well as with early …

It is estimated that 5% of pregnant women consume drugs of abuse during pregnancy.
Clinical research suggests that intake of drugs during pregnancy, such as alcohol, nicotine …

This study examined the independent and interactive effects of alcohol use disorder genome-
wide polygenic scores (AUD-PGS) and parenting and family conflict on early adolescent …

Children with ADHD show abnormal brain function and structure. Neuroimaging studies
found that stimulant medications may improve brain structural abnormalities in children with …

Background Early alcohol use initiation is one of the strongest predictors of alcohol use
disorders. Identifying modifiable risk factors for problematic alcohol use can guide …

Importance Neurobiological models have postulated shared neural mechanisms between
obsessive-compulsive disorder (OCD) and substance use disorders, but results from clinical …

Over 50% of young adults (defined as individuals aged 18–25 years) with substance use
disorders (SUDs) have at least 1 co-occurring psychiatric disorder, and the presence of …

Purpose of Review A wealth of epidemiological and cohort research, together with a healthy
dose of anecdote, has characterized late adolescence and emerging adulthood as a time of …

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition that only
rarely remits in adulthood. While several studies underlined differences between child and …